Hydroxyalkyl cellulose
US-2015342895-A1 · Dec 3, 2015 · US
Agent for evading immune response
US9387175B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9387175-B2 |
| Application number | US-201214238616-A |
| Country | US |
| Kind code | B2 |
| Filing date | Aug 3, 2012 |
| Priority date | Aug 12, 2011 |
| Publication date | Jul 12, 2016 |
| Grant date | Jul 12, 2016 |
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Abstract
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It has been found that modification of surfaces of nanoparticles with a RolA protein decreases an immunostimulation activity of the nanoparticles on myeloid dendritic cells and also decreases phagocytosis of the nanoparticles by macrophages. The present invention provides nanoparticles being modified with a biological molecule and having an immune-response evasion function.
First claim
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The invention claimed is: 1. A composition for avoiding immunostimulation on a dendritic cell and evading phagocytosis by a macrophage, comprising a nanometer-sized metal simple substance or a nanometer-sized metal compound whose surface is modified with a RolA protein. 2. The composition according to claim 1 , wherein the RolA protein is originated from a filamentous fungus of the genus Aspergillus. 3. The composition according to clai…
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Operations & Transport · mapped topic
Operations & Transport · mapped topic
Operations & Transport · mapped topic
Chemistry & Metallurgy · mapped topic
Operations & Transport · mapped topic
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- What does patent US9387175B2 cover?
- It has been found that modification of surfaces of nanoparticles with a RolA protein decreases an immunostimulation activity of the nanoparticles on myeloid dendritic cells and also decreases phagocytosis of the nanoparticles by macrophages. The present invention provides nanoparticles being modified with a biological molecule and having an immune-response evasion function.
- Who is the assignee on this patent?
- Abe Keietsu, Kawakami Kazuyoshi, Ajiri Tadafumi, and 6 more
- What technology area does this patent fall under?
- Primary CPC classification A61K9/1676. Mapped technology areas include Human Necessities.
- When was this patent published?
- Publication date Tue Jul 12 2016 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).