Nutritional composition to promote healthy development and growth

Patent metadata

Field	Value
Publication number	US-9386794-B2
Application number	US-46402909-A
Country	US
Kind code	B2
Filing date	May 11, 2009
Priority date	Oct 24, 2008
Publication date	Jul 12, 2016
Grant date	Jul 12, 2016

Abstract

A nutritional composition having a lipid or fat; a protein source; a source of long chain polyunsaturated fatty acids which comprises docosahexanoic acid; and up to about 2.5% by weight of a source of supplemental calcium which, when dissociated, provides a cation having prebiotic functionality.

First claim

What is claimed is:

1. A nutritionally complete nutritional composition comprising
a. about 3 to about 7 g/100 kcal of a lipid or fat;
b. about 1 to about 5 g/100 kcal of a bovine milk protein source;
c. about 5 to about 100 mg/100 kcal of a source of long chain polyunsaturated fatty acids, comprising docosahexanoic acid;
d. about 1.0% to about 2.5% by weight of a source of supplemental calcium wherein at least 20% of the source of supplemental calcium comprises calcium gluconate;
e. about 0.2 to about 1.5 mg/100 kcal of a prebiotic composition comprising a plurality of oligosaccharides such that the overall fermentation rate profile of the prebiotic composition provides an increased population of beneficial bacteria in the human gut, wherein the prebiotic composition comprises polydextrose and at least 20% of an oligosaccharide which comprises galacto-oligosaccharide; and
f. a source of transforming growth factor-β (TGF-β), wherein the amount of TGF-β ranges from about 0.015 to about 0.1 pg/μg.

2. The nutritional composition of claim 1 , wherein the source of long chain polyunsaturated fatty acids further comprises arachidonic acid.

3. The nutritional composition of claim 2 , wherein the ratio of arachidonic acid to docosahexanoic acid is from about 1:3 to about 9:1.

4. The nutritional composition of claim 1 , wherein the source of supplemental calcium provides equivalent calcium bioavailability as compared to the lactate, sulfate, chloride, citrate or saccharate salts of calcium.

5. The nutritional composition of claim 1 , wherein the source of supplemental calcium further comprises a calcium source selected from the group consisting of calcium lactate, calcium sulfate, calcium chloride, calcium citrate, calcium phosphate, calcium D-saccharate, calcium aspartate, calcium propionate, and combinations thereof.

6. The nutritional composition of claim 1 , which further comprises at least one probiotic.

7. The nutritional composition of claim 6 , wherein the probiotic is selected from the group consisting of Bifidobacteria spp., Lactobacillus spp and combinations thereof.

8. The nutritional composition of claim 1 , wherein the source of supplemental calcium consists of calcium gluconate.

Assignees

• Rosales Francisco J
• Rai Gyan P
• Morris Kristin
• Banavara Dattatreya
• Van Tol Eric
• Jouni Zeina E
• Mcmahon Robert J
• Schade Deborah A
• Walker Donald Carey
• Mead Johnson Nutrition Co

Inventors

• Rosales Francisco J
• Rai Gyan P
• Morris Kristin
• Banavara Dattatreya
• Van Tol Eric
• Jouni Zeina E
• Mcmahon Robert J
• Schade Deborah A
• Walker Donald Carey

Classifications

• A61P43/00

  Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00 · CPC title

• A61P3/02

  Nutrients, e.g. vitamins, minerals · CPC title

• A61P1/00

  Drugs for disorders of the alimentary tract or the digestive system · CPC title

• A23L33/16

  Inorganic salts, minerals or trace elements · CPC title

• A23L33/12 Primary

  Fatty acids or derivatives thereof · CPC title