Mucosal tissue dressing and method of use

Patent metadata

Field	Value
Publication number	US-9381270-B2
Application number	US-201414307619-A
Country	US
Kind code	B2
Filing date	Jun 18, 2014
Priority date	Dec 31, 2007
Publication date	Jul 5, 2016
Grant date	Jul 5, 2016

Abstract

A method and apparatus for reducing or eliminating pain after surgical procedures related to mucosal tissue, including tonsillectomy, adenoidectomy, or other pharyngeal operations. Certain embodiments provide a biodegradable film or covering that serves as a mechanical barrier to reduce pain caused, for example, by friction between solid food and healing tissue in the first few days after surgery. Some embodiments may include one or more therapeutic substances for locally reducing pain, facilitating healing and/or otherwise treating mucosal tissue at or near a tonsil bed.

First claim

The invention claimed is:

1. A method of treating a tonsil removal site after a tonsillectomy procedure, the method comprising:
(a) applying a dressing over the tonsil removal site, wherein one side of the dressing is adapted to adhere to a surgical site and an opposite side of the dressing is adapted to provide abrasion resistance, the opposite side of the dressing embodying material characteristics distinct from the one side of the dressing adapted to adhere, and further wherein the dressing includes pores;
(b) polymerizing the dressing, wherein the act of polymerizing the dressing occurs after the dressing has been positioned to cover at least a portion of the tonsil removal site; and
(c) releasing a drug from the dressing.

2. The method of claim 1 , wherein at least a portion of the dressing is configured to dissolve over time.

3. The method of claim 1 , wherein the drug is released over a course of days.

4. The method of claim 1 , wherein the drug is released over a course of weeks.

5. The method of claim 1 , wherein the drug is configured to reduce pain.

6. The method of claim 1 , wherein the drug is configured to promote healing.

7. The method of claim 1 , wherein the dressing is chemically treated such that peptides or proteins are bonded to surfaces thereof.

8. The method of claim 1 , wherein the dressing has been treated by bombarding with plasma or ions.

9. The method of claim 1 , wherein the dressing includes dimples.

10. The method of claim 9 , wherein the dimples or pores are formed by molding, machining, chemically etching, or ablating a surface of the dressing.

11. The method of claim 1 , wherein the dressing includes a porous layer formed by using gas-evolution foaming techniques and incorporating and subsequently dissolving prosigens.

12. The method of claim 1 , wherein the dressing includes a fibrous surface formed by weaving or felting techniques.

13. The method of claim 1 , wherein the dressing comprises an elastic hydrated film.

14. The method of claim 1 , wherein the dressing comprises an adhesive layer and a removable backing, the method further comprises removing the backing before applying the dressing over the tonsil removal site.

15. The method of claim 1 , wherein the side of the dressing adapted to adhere to a surgical site is textured to facilitate adhesion to tissue.

16. The method of claim 1 , wherein the dressing comprises an outer rim and a concave central region, wherein the concave central region is configured to conform to a tonsil bed at the tonsil removal site.

17. A method of treating a tonsil removal site after a tonsillectomy procedure, the method comprising:
(a) positioning a dressing proximate to the tonsil removal site, wherein one side of the dressing is adapted to adhere to a surgical site and an opposite side of the dressing is adapted to provide abrasion resistance, the opposite side of the dressing embodying material characteristics distinct from the one side of the dressing adapted to adhere, and further wherein the dressing includes pores;
(b) applying the dressing, wherein the act of applying the dressing comprises applying the dressing in a liquid form to the tonsil removal site; and
(c) releasing a drug from the dressing.

18. The method of claim 17 , wherein the act of applying the dressing in a liquid form to the tonsil removal site comprises painting the dressing on the tonsil removal site.

19. The method of claim 17 , wherein the act of applying the dressing in a liquid form to the tonsil removal site comprises spraying the dressing on the tonsil removal site.

Assignees

• Acclarent Inc

Inventors

• Makower Joshua
• Chang John Y
• Muni Ketan P
• Carlyle Wenda
• Levine Howard
• Facteau William M

Classifications

• A61P17/00

  Drugs for dermatological disorders · CPC title

• A61L26/0066

  Medicaments; Biocides · CPC title

• A61L15/64

  specially adapted to be resorbable inside the body · CPC title

• Y10T156/10

  Methods of surface bonding and/or assembly therefor · CPC title

• A61L2300/406

  Antibiotics · CPC title