Method of drying bioabsorbable coating over stents

Patent metadata

Field	Value
Publication number	US-9375876-B2
Application number	US-201514928823-A
Country	US
Kind code	B2
Filing date	Oct 30, 2015
Priority date	Dec 28, 2000
Publication date	Jun 28, 2016
Grant date	Jun 28, 2016

Abstract

Various embodiments of methods for coating stents are described herein. Applying a composition including polymer component and solvent to a stent substrate followed by exposing the polymer component to a temperature equal to or greater than a Tg of the polymer component is disclosed. Repeating the applying and exposing one or more times to form a coating with the result that the solvent content of the coating after the final exposing step is at a level suitable for a finished stent is further disclosed.

First claim

What is claimed is:

1. A method of fabricating a stent, comprising:
thermally treating a stent having a stent body including a composition applied to a surface of the stent body, the composition comprising a solvent and a first bioabsorbable polymer,
wherein the stent body comprises a second bioabsorbable polymer,
wherein a glass transition temperature (Tg) of the first bioabsorbable polymer is greater than human body temperature,
wherein a process temperature of the thermal treatment is 1 to 20 deg C. above the Tg of the first bioabsorbable polymer,
wherein a duration of the thermal treatment is 5 to 30 min; and
crimping the thermally treated stent onto a catheter so that it can be delivered to and deployed at a treatment site in a blood vessel.

2. The method of claim 1 , wherein the second bioabsorbable polymer of the stent body comprises poly(L-lactide-co-caprolactone).

3. The method of claim 1 , wherein the second bioabsorbable polymer of the stent body comprises poly(L-lactide).

4. The method of claim 1 , wherein the first bioabsorbable polymer comprises poly(DL-lactide) (PDLA).

5. The method of claim 1 , wherein the thermal treatment comprises blowing a heated gas on the stent.

6. The method of claim 1 , wherein the stent is not baked after the thermal treatment.

7. The method of claim 1 , wherein no additional thermal treatment of the stent is performed after the thermal treatment.

8. The method of claim 1 , wherein the duration of the thermal treatment is 5 to 10 min.

9. The method of claim 1 , wherein the duration of the thermal treatment is 10 to 20 min.

10. The method of claim 1 , wherein the duration of the thermal treatment is 20 to 30 min.

11. The method of claim 1 , wherein the process temperature of the thermal treatment is 5 to 15 deg C. above the Tg of the first bioabsorbable polymer.

12. The method of claim 1 , wherein the process temperature of the thermal treatment is 15 to 20 deg C. above the Tg of the first bioabsorbable polymer.

Assignees

• Abbott Cardiovascular Systems

Inventors

• Chen Yung-Ming
• Van Sciver Jason
• Hossainy Syed F A
• Pacetti Stephen

Classifications

• B05D3/0473 Primary

  for heating, e.g. vapour heating · CPC title

• B05D3/0254

  After-treatment · CPC title

• A61F2/86

  Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure · CPC title

• A61F2210/0004

  bioabsorbable · CPC title

• A61F2/91

  made from perforated sheets or tubes, e.g. perforated by laser cuts or etched holes · CPC title