Process of manufacture of annexin v
US-2024116982-A1 · Apr 11, 2024 · US
Method for manufacturing protein drug
US9359397B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9359397-B2 |
| Application number | US-201214127291-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jun 22, 2012 |
| Priority date | Jun 24, 2011 |
| Publication date | Jun 7, 2016 |
| Grant date | Jun 7, 2016 |
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Abstract
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The present invention provides a method for manufacturing a virus-free protein drug, comprising (a) a filtration step of filtering a virus-containing protein solution through a small-pore size virus removal membrane to obtain a virus-free protein solution, the filtration step (a) comprising (q) a low-pressure filtration step of filtering the solution through the small-pore size virus removal membrane at a filtration pressure of 0.30 kgf/cm 2 or lower to obtain the virus-free protein solution, wherein the solution prior to filtration in the low-pressure filtration step (q) has a pH (X) and a salt ionic strength (Y (mM)) that satisfy the following equations 1 and 5: 0≦Y≦150X−590 (Equation 1) and 3.5≦X≦8.0 (Equation 5) or the following equations 4 and 5: Y=0 (Equation 4) and 3.5≦X≦8.0 (Equation 5).
First claim
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The invention claimed is: 1. A method for manufacturing a virus-free protein drug, comprising the following step (a): (a) filtering a virus containing protein solution through a small-pore size virus removal membrane to obtain a virus-free protein solution, comprising a low-pressure filtration step (q) of filtering a solution through the small-pore size virus removal membrane at a filtration pressure of 0.30 kgf/cm 2 or lower, wherein the solution prior to filtration in the…
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Operations & Transport · mapped topic
Operations & Transport · mapped topic
Chemistry & Metallurgy · mapped topic
Operations & Transport · mapped topic
Chemistry & Metallurgy · mapped topic
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- What does patent US9359397B2 cover?
- The present invention provides a method for manufacturing a virus-free protein drug, comprising (a) a filtration step of filtering a virus-containing protein solution through a small-pore size virus removal membrane to obtain a virus-free protein solution, the filtration step (a) comprising (q) a low-pressure filtration step of filtering the solution through the small-pore size virus removal me…
- Who is the assignee on this patent?
- Hongo Tomoko, Hayashida Hirohisa, Asahi Kasei Medical Co Ltd
- What technology area does this patent fall under?
- Primary CPC classification C07K1/34. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Jun 07 2016 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).