Powder composition for air polishing the surface of hard dental tissue

Patent metadata

Field	Value
Publication number	US-9358185-B2
Application number	US-201314407789-A
Country	US
Kind code	B2
Filing date	Jun 5, 2013
Priority date	Jun 18, 2012
Publication date	Jun 7, 2016
Grant date	Jun 7, 2016

Abstract

The invention is directed to a powder composition for air polishing the surface of hard dental tissue comprising a powder of water-soluble organic particles as component A, a powder of inorganic anti-caking agent(s) particles as component B and a powder of antihypersensitive acting particles as component C, the mean particle size of component A being in a range from about 15 to about 500 μm, the mean particle size of component C being in a range from about 0.5 to about 10 μm. The invention is also directed to a kit of parts comprising the powder composition and its use.

First claim

The invention claimed is:

1. A powder composition comprising:
a powder of water-soluble organic particles as component A,
a powder of inorganic anti-caking agent(s) particles as component B and
a powder of antihypersensitive acting particles as component C,
the mean particle size of component A being in a range from about 15 to about 500 μm,
the mean particle size of component C being in a range from about 0.5 to about 10 μm.

2. The powder composition as described in claim 1 being characterized by at least one of the following features:
Mass density of component A: below about 2.5 g/cm 3 ,
Mass density of component B: from about 1.2 to about 4.0 g/cm 3 ,
Mass density of component C: from about 1.2 to about 4.0 g/cm 3 .

3. The powder composition as described in claim 1 being characterized by at least one of the following features:
Water solubility of component A being greater than the water solubility of component C;
Water solubility of component B: none.

4. The powder composition as described in claim 1 being characterized by at least one of the following features:
Amount of component A: from about 50 to about 98 wt.-%,
Amount of component B: from about 0.001 to about 10 wt.-%,
Amount of component C: from about 0.1 to about 15 wt.-%, wt.-% with respect of the weight of the whole composition.

5. The powder composition as described in claim 1 , wherein component A is selected from organic acids, amino acids, sugars, the respective alkaline metal salts, alkaline earth metal salts, ammonium salts and mixtures thereof.

6. The powder composition as described in claim 1 , wherein component B is selected from fumed silica, hollow or solid glass beads and mixtures thereof.

7. The powder composition as described in claim 1 , wherein component C is selected from phosphate releasing agents, hydroxylapatite, fluoroapatite, α-, β-, amorphous-tricalciumphosphate, tricalciumphosphate coated with an organic acid, calcium hydrogen phosphate, calcium oxalate, calcium carbonate, sodium fluoride, sodium mono fluorophosphate, stannous fluoride, N,N,N′-tris(2-hydroxyethyl)-N′-octadecylpropane-1,3-diamine dihydrofluoride, Ca(HCO 3 ) 2 , NaHCO 3 and mixtures thereof.

8. The powder composition as described in claim 1 ,
component A being selected from amino acids, sugars, the respective alkaline metal salts, alkaline earth metal salts, ammonium salts and mixtures thereof,
component C being selected from phosphate releasing agents, hydroxylapatite, fluoroapatite, α-, β-, amorphous-tricalciumphosphate, tricalciumphosphate coated with fumaric acid, calcium hydrogen phosphate, calcium oxalate, calcium carbonate, sodium fluoride, sodium mono fluorophosphate, stannous fluoride, N,N,N′-tris(2-hydroxyethyl)-N′-octadecylpropane-1,3-diamine dihydrofluoride, Ca(HCO 3 ) 2 , NaHCO 3 and mixtures thereof.

9. The powder composition as described in claim 1 comprising
a powder of water-soluble organic particles as component A, the water-soluble particles being selected from amino acids and their salts, organic acids and their salts, sugars and mixtures thereof,
a powder of inorganic anti-caking agent(s) particles as component B and
a powder of antihypersensitive acting particles as component C,

the organic acids being selected from citric acid, ascorbic acid, ketoglutarsaure, pyruvic acid, lactic acid, phthalic acid, gluconic acid and mixtures thereof,
the amino acids being selected from glycine, alanine, glutamine, glutamic acid, asparagine, aspartic acid, serine, valine, leucine, iso-leucine, potassium glutamate, sodium glutamine and mixtures thereof,
the sugars being selected from xylitol, sorbitol, mannitol, erythritol, sorbitol, threitol, glucose, fructose, saccharose and mixtures thereof,
the antihypersensitive acting particles being selected from phosphate releasing agent(s), hydroxylapatite, fluoroapatite, α-, β-, amorphous-tricalciumphosphate, tricalcium phosphate coated with an organic acid, calcium hydrogen phosphate, calcium oxalate, calcium carbonate, sodium fluoride, sodium mono fluorophosphate, stannous fluoride, N,N,N′-tris(2-hydroxyethyl)-N′-octadecylpropane-1,3-diamine dihydrofluoride, Ca(HCO 3 ) 2 , NaHCO 3 and mixtures thereof.

10. The powder composition as described in claim 1 further comprising one or more adjuvants as component D selected from colourant(s), hemostatic agent(s), pharmaceutical drug(s), anti-microbial agent(s), and mixtures thereof.

11. Kit of parts comprising:
the powder composition as described in claim 1 and
a device suitable for applying the powder composition to the surface of a tooth.

12. A method of producing a powder composition to be used for air-polishing the surface of hard dental tissue, the method comprising the step of mixing components A and B with (i) tricalciumphosphate or (ii) tricalcium phosphate coated with an organic acid, components A and B being as described in claim 1 .

13. Use of a powder jet device for applying a powder composition for treating the surface of hard dental tissue, the powder composition being as described in claim 1 .

14. A process for treating the surface of hard dental tissue, the process comprising the step of applying the composition as described in claim 1 to the surface of hard dental tissue with the aid of a powder-jet device.

15. The process as described in claim 14 being characterized by at least one of the following parameters:
Dentin abrasion after treatment: below about 0.2 mm 3 ;
Powder transport rate: at least about 1 g/min;
Dentin tubuli permeability after treatment: from about 5 to about 50%.

Assignees

• 3M Innovative Properties Co

Inventors

• Haeberlein Ingo R
• Schmid Brenda
• Pfarrer Aaron M

Classifications

• A61K8/022

  Powders; Compacted Powders · CPC title

• A61Q11/00

  Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses · CPC title

• A61K8/44

  Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof · CPC title

• A61K8/25

  Silicon; Compounds thereof · CPC title

• A61K2800/412

  Microsized, i.e. having sizes between 0.1 and 100 microns · CPC title