Dyes for labelling molecular ligands
US-2016355683-A1 · Dec 8, 2016 · US
Composition, method, system and kit for optical electrophysiology
US9357924B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9357924-B2 |
| Application number | US-201213442407-A |
| Country | US |
| Kind code | B2 |
| Filing date | Apr 9, 2012 |
| Priority date | Oct 24, 2006 |
| Publication date | Jun 7, 2016 |
| Grant date | Jun 7, 2016 |
How to read this patent
A practical reading order for non-experts. Skip the full description unless you need deep technical detail.
- Title
What the patent document calls the invention.
- Abstract
A short plain-language summary of the technical disclosure.
- Assignees and inventors
Who owns or filed the patent and who is credited as inventor.
- Key dates
Filing, priority, publication, and grant dates set the timeline.
- First independent claim
The legal scope of protection — read this for what is actually claimed.
- CPC / IPC classifications
Technology tags used to group this patent with similar filings.
- Citations and related patents
Prior art links and similar publications in this corpus.
Abstract
Official abstract text for this publication.
The present invention provides a method of optical electrophysiological probing, including: providing a fluorescing chemical probe; contacting a thick portion of tissue with the fluorescing chemical probe to create a thick portion of treated tissue; applying a first range of wavelengths of electromagnetic radiation to the treated portion of tissue; and detecting a plurality of depth-specific emission wavelengths emitted from the thick portion of treated tissue.
First claim
Opening claim text (preview).
We claim: 1. An optically mapping composition comprising a voltage-sensitive dye of the formula: wherein R 1 is a first hydrocarbon group that is a butyl group; R 2 is a second hydrocarbon group that is a butyl group; and R 3 is a butyl sulfonate polar group. 2. The composition of claim 1 , further comprising a delivery agent that is at least one of a physiologically acceptable adjuvant, solvent, substrate, or diluent. 3. The composition of claim 2 , wherein the delivery agent is selected from the group consisting of: Pluronic F-127, Pluronic L64, cyclodextrin, gamma cyclodextrin, dimethylsulfoxide, ethanol, and combinations thereof.
Assignees
Inventors
Classifications
- C09B23/0075Primary
the polymethine chain being part of an heterocyclic ring · CPC title
Human Necessities · mapped topic
spatially resolved investigating of object in scattering medium (in vivo A61B) · CPC title
- A61B5/0059Primary
using light, e.g. diagnosis by transillumination, diascopy, fluorescence (photoacoustic A61B5/0093; optical measurement of heart rate A61B5/02416; optical measurement of blood flow A61B5/0261; optical measurement of analytes A61B5/1455) · CPC title
characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules · CPC title
Patent family
Related publications grouped by family.
External sources
Frequently asked questions
Answers are generated from the same data shown on this page.
- What does patent US9357924B2 cover?
- The present invention provides a method of optical electrophysiological probing, including: providing a fluorescing chemical probe; contacting a thick portion of tissue with the fluorescing chemical probe to create a thick portion of treated tissue; applying a first range of wavelengths of electromagnetic radiation to the treated portion of tissue; and detecting a plurality of depth-specific em…
- Who is the assignee on this patent?
- Pertsov Arkady M, Matiukas Arvydas, Loew Leslie M, and 3 more
- What technology area does this patent fall under?
- Primary CPC classification C09B23/0075. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Jun 07 2016 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).