Ion guide or filters with selected gas conductance

Patent metadata

Field	Value
Publication number	US-9355831-B2
Application number	US-201414293073-A
Country	US
Kind code	B2
Filing date	Jun 2, 2014
Priority date	Jun 3, 2013
Publication date	May 31, 2016
Grant date	May 31, 2016

Abstract

Certain embodiments described herein are directed to rod assemblies such as, for example, quadrupole, hexapole and octupole rod assemblies. In some instances, the rod assemblies include at least one pole comprising an integral fluid path configured to fluidically couple an ion volume formed by the assembly to an outer volume of the assembly to remove fluid within the ion volume to the outer volume while containing ions of a selected mass-to-charge range.

First claim

The invention claimed is:

1. A device comprising a multipole assembly comprising a plurality of poles, in which at least one of the poles of the multipole assembly comprises an integral fluid path that fluidically couples an ion volume formed by the poles of the multipole assembly to an outer volume of the multipole assembly, in which the integral fluid path is configured to decrease a pressure of a second section of the multipole assembly downstream of a first section of the multipole assembly comprising the integral fluid path by drawing gas from the ion volume into the outer volume, in which the first section and the second section are electrically coupled to each other to permit an effective field to be provided by the multipole assembly to transmit ions through the first section and the second section of the multipole assembly.

2. The device of claim 1 , in which the poles of the multipole assembly are configured together to transmit ions of a selected mass-to-charge ratio range.

3. The device of claim 1 , in which the first section comprises a width at a first end of the first section that is less than a width at a second end of the first section.

4. The device of claim 3 , in which the second section comprises a second integral fluid flow path.

5. The device of claim 1 , in which at least two opposite poles of the multipole assembly are configured with an integral fluid path effective to remove fluid from the ion volume to the outer volume.

6. The device of claim 1 , in which multipole assembly comprises at least separate three sections electrically coupled to each other with each section of the multipole assembly configured with an integral fluid path effective to remove fluid from the ion volume to the outer volume to decrease pressure downstream of each section of the multipole assembly.

7. The device of claim 5 , in which the opposite poles of the multipole assembly comprise an integral fluid path that each comprise a width at a first end that is less than a width at a second end.

8. The device of claim 7 , in which the opposite poles comprising the integral fluid path each comprise two or more sections electrically coupled to each other.

9. The device of claim 8 , in which each of the sections of each of the opposite poles comprises an integral fluid path effective to remove gas from the ion volume to the outer volume.

10. The device of claim 1 , in which the integral fluid path is arranged at a non-orthogonal angle to an ion travel axis of the multipole assembly.

11. The device of claim 1 , in which the multipole assembly is configured as a quadrupole assembly.

12. The device of claim 11 , in which each of first, second, third and fourth poles of the quadrupole assembly comprises a first section comprising an integral fluid path that fluidically couples the ion volume formed by the poles of the quadrupole assembly to an outer volume of the quadrupole assembly.

13. The device of claim 12 , in which each integral fluid path is arranged at a non-orthogonal angle to an ion travel axis of the quadrupole assembly.

14. The device of claim 1 , in which the multipole assembly is configured as a hexapole assembly.

15. The device of claim 14 , in which each of first, second, third, fourth, fifth and sixth poles of the hexapole assembly comprises a first section comprising an integral fluid path that fluidically couples the ion volume formed by the poles of the hexapole assembly to an outer volume of the hexapole assembly.

16. The device of claim 15 , in which each integral fluid path is arranged at a non-orthogonal angle to an ion travel axis of the hexapole assembly.

17. The device of claim 1 , in which the multipole assembly is configured as an octupole assembly.

18. The device of claim 17 , in which each of first, second, third, fourth, fifth, sixth, seventh and eighth poles of the octupole assembly comprises a first section comprising an integral fluid path that fluidically couples the ion volume formed by the poles of the octupole assembly to an outer volume of the octupole assembly.

19. The device of claim 18 , in which each integral fluid path is arranged at a non-orthogonal angle to an ion travel axis of the octupole assembly.

20. The device of claim 1 , in which the integral fluid path of the first section comprises a plurality of individual apertures each comprising a respective serration, in which each of the plurality of individual apertures in the first section comprises a different size from other apertures in the first section.

Assignees

• Steiner Urs
• Perkinelmer Health Sci Inc

Inventors

• Steiner Urs

Classifications

• H01J49/063 Primary

  Multipole ion guides, e.g. quadrupoles, hexapoles · CPC title

• H01J49/421

  Mass filters, i.e. deviating unwanted ions without trapping · CPC title

• H01J49/4255

  with particular constructional features · CPC title

• H01J49/24

  Vacuum systems, e.g. maintaining desired pressures · CPC title