Macrocyclic peptidomimetic protease inhibitor and use thereof
US-2024327458-A1 · Oct 3, 2024 · US
US9353120B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9353120-B2 |
| Application number | US-201514645967-A |
| Country | US |
| Kind code | B2 |
| Filing date | Mar 12, 2015 |
| Priority date | Sep 9, 2009 |
| Publication date | May 31, 2016 |
| Grant date | May 31, 2016 |
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Provided are a cross-bridged tetraaza macrocyclic compound of a novel structure that can be used, for example, as a contrast agent for diagnostic imaging or a radiopharmaceutical and a method for preparing the same. The disclosed tetraaza macrocyclic compound is able to form a stable metal complex at a lower temperature and allows easy conjugation with a bioactive substance or a chemically active substance, when compared to the existing cross-bridged tetraaza macrocyclic compounds.
Opening claim text (preview).
The invention claimed is: 1. A tetraaza macrocyclic compound represented by Chemical Formula 1 or a pharmaceutically acceptable salt thereof:
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Antiallergic agents (antiasthmatic agents A61P11/06; ophthalmic antiallergics A61P27/14) · CPC title
Drugs for immunological or allergic disorders · CPC title
the peptide being a RGD-containing peptide · CPC title
Bridged systems · CPC title
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