Volumetric Imaging
US-2024418652-A1 · Dec 19, 2024 · US
US9348128B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9348128-B2 |
| Application number | US-201314394009-A |
| Country | US |
| Kind code | B2 |
| Filing date | May 3, 2013 |
| Priority date | May 7, 2012 |
| Publication date | May 24, 2016 |
| Grant date | May 24, 2016 |
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A microscope for high spatial resolution imaging a structure of interest in a sample comprising a substance having a first state with first spectral properties and a second state with second spectral properties, the microscope comprising: an objective-lens assembly, a wave front modulating optical device adapted to spatially vary an intensity of a transfer light beam, a probe detector arranged to detect an optical measurement signal from a portion of the substance in the second state and placed in an area of the transfer light beam with an intensity adapted not to transfer the substance between the first and second states said microscope comprising a phase contrast microscopy system which includes an intensity detector arranged to detect an intensity of an illuminating light beam after said illuminating light beam has passed through the sample, the objective-lens assembly and the wave front modulating optical device.
Opening claim text (preview).
The invention claimed is: 1. A microscope for high spatial resolution imaging a structure of interest in a sample comprising a substance, said substance having a first state with first spectral properties and a second state with second spectral properties, the microscope comprising: an objective-lens assembly having first and second sides opposite to each other, and presenting first and second focal planes respectively on said first and second sides, the sample being intended to b…
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