Automatic analyzer

Patent metadata

Field	Value
Publication number	US-9347966-B2
Application number	US-86779509-A
Country	US
Kind code	B2
Filing date	May 1, 2009
Priority date	May 8, 2008
Publication date	May 24, 2016
Grant date	May 24, 2016

Abstract

In the field of automatic analyzers, as items to be analyzed are increase, various reagents differing in such properties as liquid viscosity and contact angle are being used more frequently, and this trend is expected to continue. Also, reagents now take various forms (e.g., a concentrated reagent to be diluted by the water of an automatic analyzer), and so does dilution water. Such being the case, the invention provides an automatic analyzer capable of sufficient stirring regardless of items to be analyzed. To sufficiently stir a substance to which a reagent has been added, the automatic analyzer is designed to alter stirring conditions after a given amount of time has passed since the addition of that reagent.

First claim

The invention claimed is:

1. An automatic analyzer, comprising:
a control unit;
a first stirring mechanism, having a plurality of first electrodes, configured to stir a mixed liquid including a sample, a reagent, and dilution water contained in a reaction container;
a second stirring mechanism, having a plurality of second electrodes, configured to stir the mixed liquid in the reaction container;
a reaction disk configured to hold the reaction container at a predetermined position on the reaction disk;
a drive mechanism configured to rotate the reaction disk; and
a storage unit configured to store a first stirring intensity condition, which are parameters indicating one or more of the first electrodes that are enabled and a voltage applied to the one or more first electrodes that are enabled, and a second stirring intensity condition, which are parameters indicating one or more of the second electrodes that are enabled and a voltage applied to the one or more second electrodes that are enabled,
wherein the control unit is programmed to receive the first stirring intensity condition and the second stirring intensity condition from the storage unit,
wherein the control unit is programmed to control the drive mechanism to rotate the reaction disk so the predetermined position holding the reaction container is moved to a first position in front of the first stirring mechanism,
wherein the control unit is programmed to control the first stirring mechanism according to the first stirring intensity condition,
wherein the control unit is programmed to control the drive mechanism to rotate the reaction disk so the predetermined position holding the reaction container is moved to a second position in front of the second stirring mechanism,
wherein the control unit is programmed to control the second stirring mechanism according to the second stirring intensity condition,
wherein the first stirring intensity condition is different than the second stirring intensity condition, and
wherein the control unit is programmed to select the first stirring intensity condition from a set of possible first stirring intensity conditions based on data indicating an amount of the dilution water in the reaction container, and the control unit is programmed to select the second stirring intensity condition from a set of possible second stirring intensity conditions based on data of properties of the mixed liquid having been stirred by the first stirring mechanism.

2. The automatic analyzer of claim 1 ,
wherein the control unit is programmed to control the first stirring mechanism according to the first stirring intensity condition for a first predetermined amount of time, and
wherein the control unit is programmed to control the second stirring mechanism according to the second stirring intensity condition for a second predetermined amount of time.

3. The automatic analyzer of claim 1 ,
wherein the reagent in the mixed liquid is a reagent of a plurality of reagents held in a reagent disk,
wherein the control unit is programmed to select the first stirring intensity condition from the set of first stirring intensity conditions based on properties of the reagent in the mixed liquid, which are stored in the storage unit for each of the plurality of reagents.

4. The automatic analyzer of claim 1 ,
wherein the first stirring mechanism includes a first piezoelectric element having the plurality of first electrodes disposed on the first piezoelectric element,
wherein the second stirring mechanism includes a second piezoelectric element having the plurality of second electrodes disposed on the second piezoelectric element, and
wherein the control unit is programmed to select the first stirring intensity condition from the set of possible first stirring intensity conditions and the second stirring intensity condition from the set of possible second stirring intensity conditions based on data indicating a viscosity and data indicating an amount of the mixed liquid.

5. The automatic analyzer according to claim 1 ,
wherein the voltage applied to the one or more first electrodes that are enabled in the first stirring intensity condition is greater than the voltage applied to the one or more second electrodes that are enabled in the second stirring intensity condition.

6. An automatic analyzer, comprising:
a control unit;
a first stirring mechanism, having a plurality of first electrodes to stir a mixed liquid including a sample and a reagent contained in a reaction container;
a second stirring mechanism, having a plurality of second electrodes, configured to stir the mixed liquid in the reaction container;
a reaction disk configured to hold the reaction container at a predetermined position on the reaction disk;
a drive mechanism configured to rotate the reaction disk; and
a storage unit configured to store a first stirring intensity condition, which are parameters indicating one or more of the first electrodes that are enabled and a voltage applied to the one more first electrodes that are enabled, and a second stirring intensity condition, which are parameters indicating one or more of the second electrodes that are enabled and a voltage applied to the one or more second electrodes that are enabled,
wherein the control unit is programmed to receive the first stirring intensity condition and the second stirring intensity condition from the storage unit,
wherein the control unit is programmed to control the drive mechanism to rotate the reaction disk so the predetermined position holding the reaction container is moved to a first position in front of the first stirring mechanism,
wherein the control unit is programmed to control the first stirring mechanism according to the first stirring intensity condition for a predetermined amount of time,
wherein the control unit is programmed to control the drive mechanism to rotate the reaction disk so the predetermined position holding the reaction container is moved to a second position in front of the second stirring mechanism,
wherein the control unit is programmed to control the second stirring mechanism according to the second stirring intensity condition,
wherein the first stirring intensity condition is different than the second stirring intensity condition, and
wherein the control unit is programmed to select the first stirring intensity condition from a set of possible first stirring intensity conditions based on data indicating an amount of the dilution water in the reaction container, and the control unit is programmed to select the second stirring intensity condition from a set of possible second stirring intensity conditions based on data of properties of the mixed liquid having been stirred by the first stirring mechanism.

7. An automatic analyzer, comprising:
a control unit;
a first ultrasonic stirrer, having a plurality of electrodes, to stir a mixed liquid including a sample, a reagent and dilution water contained in a reaction container;
a second ultrasonic stirrer, having a plurality of second electrodes, configured to stir the mixed liquid in the reaction container;
a reaction disk configured to hold the reaction container at a predetermined position on the reaction disk;
a drive mechanism configured to rotate the reaction disk; and
a storage unit configured to store a first stirring intensity, which are parameters indicating one or more of the first electrodes that are enabled and a voltage applied to the one or more first electrodes that are enabled, and a second stirring intensity condition, which are parameters indicating one or more second electrodes that are enabled and a voltage applied to the one or more second electrodes that are enabled,
wherein the control unit is programmed to receive the first

Assignees

• Sugiyama Chie
• Matsubara Shigeki
• Hitachi High Tech Corp

Inventors

• Sugiyama Chie
• Matsubara Shigeki

Classifications

• G01N35/1002 Primary

  Reagent dispensers · CPC title

• B01F7/161

  Operations & Transport · mapped topic

• G01N2035/00514

  Stationary mixing elements · CPC title

• Y10T436/25

  including sample preparation · CPC title

• B01F11/0283

  Operations & Transport · mapped topic