Pyrazolopyrimidine compounds
US-2015225403-A1 · Aug 13, 2015 · US
6-amino-purin-8-one compounds
US9346806B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9346806-B2 |
| Application number | US-201113272956-A |
| Country | US |
| Kind code | B2 |
| Filing date | Oct 13, 2011 |
| Priority date | Aug 11, 2008 |
| Publication date | May 24, 2016 |
| Grant date | May 24, 2016 |
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- Title
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Abstract
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Compounds of formula (I): wherein R 1 is C 1-6 alkylamino, C 1-6 alkoxy, or C 3-7 cycloalkyloxy; m is an integer having a value of 3 to 6; n is an integer having a value of 0 to 4; and salts thereof are inducers of human interferon. Compounds which induce human interferon may be useful in the treatment of various disorders, for example the treatment of allergic diseases and other inflammatory conditions for example allergic rhinitis and asthma, the treatment of infectious diseases and cancer, and may also be useful as vaccine adjuvants.
First claim
Opening claim text (preview).
What is claimed is: 1. A method of treatment of asthma, which method comprises administering to a human subject in need thereof the compound 6-amino-2-{[(1S)-1-methylbutyl]oxy}-9-[5-(1-piperidinyl)pentyl]-7,9-dihydro-8H-purin-8-one, or a pharmaceutically acceptable salt thereof. 2. A method of treatment of asthma, which method comprises administering to a human subject in need thereof the compound 6-amino-2-{[(1S)-1-methylbutyl]oxy}-9-[5-(1-piperidinyl)pentyl]-7,9-dihydro-8H-purin-8-one.
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Classifications
Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] · CPC title
- C07D473/18Primary
one oxygen and one nitrogen atom, e.g. guanine · CPC title
Drugs for immunological or allergic disorders · CPC title
- A61K31/522Primary
having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir · CPC title
Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics · CPC title
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- What does patent US9346806B2 cover?
- Compounds of formula (I): wherein R 1 is C 1-6 alkylamino, C 1-6 alkoxy, or C 3-7 cycloalkyloxy; m is an integer having a value of 3 to 6; n is an integer having a value of 0 to 4; and salts thereof are inducers of human interferon. Compounds which induce human interferon may be useful in the treatment of various disorders, for example the treatment of allergic disea…
- Who is the assignee on this patent?
- Biggadike Keith, Coe Diane Mary, Lewell Xiao Qing, and 4 more
- What technology area does this patent fall under?
- Primary CPC classification C07D473/18. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue May 24 2016 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 1 related publication on this page (citations in our corpus or others sharing the same primary CPC).