KCa3.1 INHIBITORS FOR PODOCYTE PROTECTION
US-2024391880-A1 · Nov 28, 2024 · US
Purification method
US9346771B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9346771-B2 |
| Application number | US-201514619871-A |
| Country | US |
| Kind code | B2 |
| Filing date | Feb 11, 2015 |
| Priority date | Oct 8, 2009 |
| Publication date | May 24, 2016 |
| Grant date | May 24, 2016 |
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- Title
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Abstract
Official abstract text for this publication.
A diagnostic imaging agent useful for positron emission tomography (PET) imaging as well as to improved hardware for producing such imaging agents is described. Flutemetamol ( 18 F) Injection for the imaging of β-amyloid plaques in the brain and methods and devices for preparing same are described including the automated synthesis and purification of [ 18 F]flutemetamol by means of solid phase extraction (SPE).
First claim
Opening claim text (preview).
The invention claimed is: 1. A cassette for use in an automated radiosynthesis apparatus comprising: (i) a vessel containing a crude product reaction mixture comprising [18F]flutemetamol; (ii) a first reverse phase solid phase extraction (SPE) cartridge; (iii) means for washing and eluting said first reverse phase SPE cartridge; (iv) a normal phase SPE cartridge; (v) a second reverse phase SPE cartridge; and (vi) means for rinsing and eluting said second reverse phase SPE cartridge. 2. The cassette according to claim 1 wherein said first reverse phase SPE cartridge and said second reverse phase SPE cartridge are each a C30 SPE cartridge. 3. The cassette according to claim 2 wherein said first reverse phase SPE cartridge and said second reverse phase SPE cartridge are each pre-conditioned with acetonitrile and water.
Assignees
Inventors
Classifications
- C07D277/66Primary
with aromatic rings or ring systems directly attached in position 2 · CPC title
Heterocyclic compounds · CPC title
carboxylic acid carriers, fatty acids (amino acids A61K51/0406) · CPC title
Purification; Separation (separation of optically-active compounds C07B57/00); Stabilisation; Use of additives · CPC title
characterised by the separation mechanism · CPC title
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- What does patent US9346771B2 cover?
- A diagnostic imaging agent useful for positron emission tomography (PET) imaging as well as to improved hardware for producing such imaging agents is described. Flutemetamol ( 18 F) Injection for the imaging of β-amyloid plaques in the brain and methods and devices for preparing same are described including the automated synthesis and purification of [ 18 F]flutemetamol by means of solid phase …
- Who is the assignee on this patent?
- Ge Healthcare Ltd
- What technology area does this patent fall under?
- Primary CPC classification C07D277/66. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue May 24 2016 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).