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US-2024424050-A1 · Dec 26, 2024 · US
Agent for promoting proliferation of bifidobacteria
US9345743B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9345743-B2 |
| Application number | US-201214346050-A |
| Country | US |
| Kind code | B2 |
| Filing date | Aug 24, 2012 |
| Priority date | Dec 19, 2011 |
| Publication date | May 24, 2016 |
| Grant date | May 24, 2016 |
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- Title
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- Abstract
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Abstract
Official abstract text for this publication.
A peptide dimer comprising a peptide consisting of the amino acid sequence of SEQ ID NO: 1 and a peptide consisting of any one of the amino acid sequences of SEQ ID NOS: 2 to 4, wherein the peptide consisting of the amino acid sequence of SEQ ID NO: 1 and the peptide consisting of any one of the amino acid sequences of SEQ ID NOS: 2 to 4 are bound through a disulfide bond between a cysteine residue of each peptide is used as an active ingredient of an agent for promoting proliferation of one or more bacterium selected from the group consisting of Bifidobacterium infantis and Bifidobacterium breve.
First claim
Opening claim text (preview).
What is claimed is: 1. A composition comprising a peptide dimer and 10 to 10 5 CFU of one or more bacterium selected from the group consisting of Bifidobacterium infantis and Bifidobacterium breve per 1 μg of the peptide dimer,wherein: the peptide dimer comprises a peptide consisting of the amino acid sequence of SEQ ID NO: 1, and a peptide consisting of the amino acid sequence of SEQ ID NO: 2, and wherein the peptide consisting of the amino acid sequence of SEQ ID NO: 1 and the peptide consisting of the amino acid sequences of SEQ ID NO: 2 are bound through a disulfide bond between a cysteine residue of each peptide. 2. The composition according to claim 1 , wherein the composition is a drug. 3. The composition according to claim 1 , wherein the composition is a food or drink. 4. A method for improving intestinal bacterial flora, and treating diarrhea, constipation, obesity, or inflammatory bowel disease, comprising: administering the composition according to claim 1 to an animal or a human in need thereof. 5. The method according to claim 4 , wherein the dosage of administration of the composition is the range of 10 to 5000μg/kg/dose in terms of the amount of the peptide dimer at a frequency of once/3 days to 5 times/day.
Assignees
Inventors
Classifications
Adding ingredients (adding preservatives A23B70/10) · CPC title
Transferrins, e.g. lactoferrins, ovotransferrins · CPC title
- A61K38/10Primary
Peptides having 12 to 20 amino acids {(A61K38/043 - A61K38/046 take precedence)} · CPC title
Bacteria or derivatives thereof, e.g. probiotics · CPC title
Peptides; Protein hydrolysates · CPC title
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- What does patent US9345743B2 cover?
- A peptide dimer comprising a peptide consisting of the amino acid sequence of SEQ ID NO: 1 and a peptide consisting of any one of the amino acid sequences of SEQ ID NOS: 2 to 4, wherein the peptide consisting of the amino acid sequence of SEQ ID NO: 1 and the peptide consisting of any one of the amino acid sequences of SEQ ID NOS: 2 to 4 are bound through a disulfide bond between a cysteine res…
- Who is the assignee on this patent?
- Oda Hirotsugu, Yamauchi Koji, Sato Takumi, and 2 more
- What technology area does this patent fall under?
- Primary CPC classification A61K38/10. Mapped technology areas include Human Necessities.
- When was this patent published?
- Publication date Tue May 24 2016 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).