Modulators of Aldehyde Dehydrogenase and Methods of Use Thereof
US-2015182506-A1 · Jul 2, 2015 · US
US9345693B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9345693-B2 |
| Application number | US-201414537245-A |
| Country | US |
| Kind code | B2 |
| Filing date | Nov 10, 2014 |
| Priority date | Sep 8, 2008 |
| Publication date | May 24, 2016 |
| Grant date | May 24, 2016 |
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The present invention provides compounds that function as modulators of aldehyde dehydrogenase activity; and pharmaceutical compositions comprising the compounds. The present invention provides therapeutic methods involving administering a subject compound, or a subject pharmaceutical composition.
Opening claim text (preview).
What is claimed is: 1. A method of treating an ALDH-mediated disorder selected from alcohol intolerance, alcohol addiction, alcohol abuse disorder, methanol poisoning, and ethylene glycol monomethyl ether poisoning, the method comprising administering to individual in need thereof a compound Formula I: wherein: each of R 1 , R 2 , and R 3 is independently selected fr…
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