Retinal prosthesis system using nanowire light detector, and manufacturing method thereof

Patent metadata

Field	Value
Publication number	US-9345568-B2
Application number	US-201213983518-A
Country	US
Kind code	B2
Filing date	May 4, 2012
Priority date	Mar 23, 2011
Publication date	May 24, 2016
Grant date	May 24, 2016

Abstract

A retinal prosthesis system can comprise: a flexible substrate; a nanowire light detector which is placed on the substrate, and comprises one or more nanowires of which the resistance changes according to the applied light; one or more micro-electrodes which are placed on the substrate, are electrically connected to the nanowire light detector, and come in contact with retinal cells; and an electric power supply source for applying electric power to the nanowire light detector and the micro-electrodes. The retinal prosthesis system can be implemented into a very thin and flexible substrate type high resolution retinal system by manufacturing a nanowire light detector on a substrate in which micro-electrodes are implemented.

First claim

The invention claimed is:

1. A retinal prosthesis system, comprising:
a flexible substrate;
a nanowire photodetector disposed on the flexible substrate and having a plurality of nanowires whose resistance varies according to an applied light;
a plurality of micro electrodes arranged in an array pattern disposed on the flexible substrate, the micro electrode array electrically connected to the nanowire photodetector and comprising a retina-engaging portion protruding in a vertical direction from a surface of the flexible substrate for contacting a retina cell; and
a discrete power source for providing the nanowire photodetector and the micro electrode array with a stimulation signal waveform, the power source further including a battery,
wherein the nanowire photodetector comprises a plurality of column structures each having a nanowire, wherein each column structure includes a first portion having a first width and extending in one direction and a second portion having a second width smaller than the first width and supporting the first portion, and wherein each column structure further includes an oxide film disposed on the first portion and the second portion so that the first portion has each nanowire and the oxide film surrounds each nanowire,
wherein the nanowire photodetector modulates a stimulation signal waveform generated by the power source according to the applied light and transmits the modulated signal to the micro electrode array, and
wherein the micro electrode array receives the signal modulated by the nanowire photodetector and applies the modulated signal to the retina cell to stimulate the retina cell.

2. The retinal prosthesis system according to claim 1 , wherein each nanowire includes silicon.

3. The retinal prosthesis system according to claim 1 , wherein the substrate includes polymer or polyimide.

4. The retinal prosthesis system according to claim 1 , further comprising a nanowire field effect transistor electrically connected to the nanowire photodetector to amplify a signal of the nanowire photodetector.

5. The retinal prosthesis system according to claim 1 , wherein the substrate, the nanowire photodetector and the micro electrode array are configured to be transplanted in a living body.

Assignees

• Cho Dong Il
• Jung Suk Won
• Lee Sang Min
• Park Sun Kil
• Ahn Jae Hyun
• Hong Seok Jun
• Yoo Hyoung Jung
• Snu R&Db Foundation

Inventors

• Cho Dong Il
• Jung Suk Won
• Lee Sang Min
• Park Sun Kil
• Ahn Jae Hyun
• Hong Seok Jun
• Yoo Hyoung Jung

Classifications

• H10F99/00

  Subject matter not provided for in other groups of this subclass · CPC title

• A61N1/36046 Primary

  of the eye · CPC title

• A61N1/0543

  Retinal electrodes · CPC title

• A61F2/14 Primary

  Eye parts, e.g. lenses or corneal implants; Artificial eyes · CPC title

• A61N1/04

  Electrodes {(electrosurgical electrodes A61B18/14)} · CPC title