Systems and methods for mechanogenetic functional ultrasound imaging
US-12172037-B2 · Dec 24, 2024 · US
US9345450B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9345450-B2 |
| Application number | US-201314135063-A |
| Country | US |
| Kind code | B2 |
| Filing date | Dec 19, 2013 |
| Priority date | Dec 21, 2012 |
| Publication date | May 24, 2016 |
| Grant date | May 24, 2016 |
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An ultrasound transducer for use in intra-vascular ultrasound (IVUS) imaging systems including a single crystal composite (SCC) layer is provided. The transducer has a front electrode on a side of the SCC layer; and a back electrode on the opposite side of the SCC layer. The SCC layer may have a dish shape including pillars made of a single crystal piezo-electric material embedded in a polymer matrix. Also provided is an ultrasound transducer as above, with the back electrode split into two electrodes electrically decoupled from one another. A method of forming an ultrasound transducer as above is also provided. An IVUS imaging system is provided, including an ultrasound transducer rotationally disposed within an elongate member; an actuator; and a control system controlling activation of the ultrasound transducer to facilitate imaging.
Opening claim text (preview).
What is claimed is: 1. A method of forming a single ultrasound transducer for use in IVUS imaging systems, the method comprising: etching a single crystal; placing a polymer layer on the etched single crystal to form a single crystal composite (SCC); forming the polymer layer to a first thickness; placing a first electrode on a first side of the SCC; forming the SCC to a second thickness; placing a second electrode on a second side of the SCC; and deforming the SCC to define a concave surface and an opposing convex surface, the deforming including forming an aperture having a diameter of an integer multiple of wavelengths of a center frequency of an ultrasound signal transmitted by the single transducer. 2. The method of claim 1 further comprising forming an index matching layer above the SCC layer, the index matching layer having a thickness of about ¼ wavelength of a center frequency of an ultrasound signal transmitted by the transducer. 3. The method of claim 1 wherein the deforming the SCC includes placing the SCC on a molded tip. 4. The method of claim 1 wherein deforming the SCC comprises forming a section of a sphere, the section having a depth of approximately 20 μm. 5. The method of claim 1 wherein the etching the single crystal comprises deep reactive ion etching. 6. The method of claim 1 wherein the etching the single crystal comprises defining a plurality of pillars. 7. The method of claim 6 , wherein each of the pillars has a thickness-to-width aspect ratio of at least 2. 8. The method of claim 6 , wherein each of the pillars has a cross section on a surface of the SCC with a shape selected from the group consisting of a circle, a square, a rectangle, and a figure from a random pattern. 9. The method of claim 1 , wherein the placing the second electrode on the second side of the SCC includes placing two electrodes electrically decoupled from one another on the second side of the SCC. 10. The method of claim 1 , wherein the convex surface of the SCC has a center of curvature along an axis of an ultrasound beam of the single ultrasound transducer. 11. A method of forming an intravascular ultrasound catheter, the method comprising: providing a single ultrasound transducer having: a single crystal composite (SCC) layer; a front electrode on a side of the SCC layer; and a back electrode on the opposite side of the SCC layer; wherein: the SCC layer includes pillars made of a single crystal piezoelectric material; the pillars are embedded in a polymer matrix; and the SCC layer has a concave upper surface and an opposing convex lower surface, and an aperture having a diameter of an integer multiple of wavelengths of a center frequency of an ultrasound signal transmitted by the single transducer; and coupling the single ultrasound transducer to a distal portion of an intravascular catheter. 12. The method of claim 11 , wherein the coupling the single ultrasound transducer to the distal portion of the intravascular catheter includes coupling the single ultrasound transducer to a rotatable drive shaft. 13. The method of claim 11 , wherein each of the pillars of the provided single ultrasound transducer has a thickness-to-width aspect ratio of at least 2. 14. The method of claim 11 , wherein each of the pillars of the provided single ultrasound transducer has a cross section on a surface of the SCC with a shape selected from the group consisting of a circle, a square, a rectangle, and a figure from a random pattern. 15. The method of claim 11 , wherein the back electrode of the provided single ultrasound transducer includes two electrodes electrically decoupled from one another. 16. The method of claim 11 , wherein the convex surface of the SCC of the provided single ultrasound transducer has a center of curvature along an axis of an ultrasound beam of the single ultrasound transducer.
Details of catheter construction · CPC title
Echo-tomography · CPC title
on one surface · CPC title
which is used as, or combined with, an impedance matching layer · CPC title
in body cavities or body tracts, e.g. by using catheters · CPC title
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