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Method of modulating the activity of a nucleic acid molecule
US9340591B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9340591-B2 |
| Application number | US-58801609-A |
| Country | US |
| Kind code | B2 |
| Filing date | Sep 30, 2009 |
| Priority date | Mar 30, 2007 |
| Publication date | May 17, 2016 |
| Grant date | May 17, 2016 |
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Abstract
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The present invention relates, in general, to agents that modulate the pharmacological activity of nucleic acid molecules and, in particular, to agents that bind therapeutic or diagnostic nucleic acid molecules in a sequence independent manner and modulate (e.g., inhibit or reverse) their activity. The invention also relates to compositions comprising such agents and to methods of using same.
First claim
Opening claim text (preview).
What is claimed is: 1. A method of inhibiting the activity of a nucleic acid molecule (NAM) that binds to a target molecule and elicits a pharmacological effect, said method comprising contacting said NAM with a universal antidote (UA) under conditions such that said UA binds to said NAM and modifies the interaction between said NAM and said target, wherein said binding of said UA to said NAM is independent of the nucleotide sequence of said NAM and wherein said UA is a pharmaceuti…
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Physics · mapped topic
Physics · mapped topic
Physics · mapped topic
Physics · mapped topic
Chemistry & Metallurgy · mapped topic
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Frequently asked questions
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- What does patent US9340591B2 cover?
- The present invention relates, in general, to agents that modulate the pharmacological activity of nucleic acid molecules and, in particular, to agents that bind therapeutic or diagnostic nucleic acid molecules in a sequence independent manner and modulate (e.g., inhibit or reverse) their activity. The invention also relates to compositions comprising such agents and to methods of using same.
- Who is the assignee on this patent?
- Sullenger Bruce A, Oney Sabah, Lam Tung Suet Ruby, and 2 more
- What technology area does this patent fall under?
- Primary CPC classification C07K14/46. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue May 17 2016 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).