Methods of treating depression and other related diseases

Patent metadata

Field	Value
Publication number	US-9340576-B2
Application number	US-201313909712-A
Country	US
Kind code	B2
Filing date	Jun 4, 2013
Priority date	Oct 5, 2009
Publication date	May 17, 2016
Grant date	May 17, 2016

Abstract

The invention relates to methods for treating depression, anxiety, and other related diseases by administering a peptide NMDAR partial agonist.

First claim

What is claimed is:

1. A method for treating dysthymic disorder in a patient in need thereof, comprising administering to said patient a 1 mg/kg to about 10 mg/kg dose of a compound represented by:

or pharmaceutically acceptable salts, homologs, or hydrates thereof.

2. The method of claim 1 , comprising administering the composition every week or every two weeks to said patient.

3. The method of claim 1 , wherein administration of a single dose is effective for up to 4 days.

4. The method of claim 1 , further comprising administering another antidepressant drug.

5. he method of claim 2 , further comprising administering another antidepressant drug.

6. A method for treating dysthymic disorder in a patient in need thereof, comprising administering to said patient a pharmaceutically acceptable composition comprising:
a 1 mg/kg to about 10 mg/kg dose of a compound represented by:

 and
an excipient.

7. A method for treating dysthymic disorder in a patient in need thereof, comprising administering to said patient a 1 mg/kg to about 10 mg/kg dose of a compound represented by:

Assignees

• Moskal Joseph
• Univ Northwestern

Inventors

• Moskal Joseph

Classifications

• A61K45/06

  Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca · CPC title

• A61K38/07

  Tetrapeptides · CPC title

• A61P25/22

  Anxiolytics · CPC title

• A61P25/24

  Antidepressants · CPC title

• A61P25/18

  Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia · CPC title