Retractable drug delivery system and method

Patent metadata

Field	Value
Publication number	US-9339630-B2
Application number	US-38907009-A
Country	US
Kind code	B2
Filing date	Feb 19, 2009
Priority date	Feb 19, 2009
Publication date	May 17, 2016
Grant date	May 17, 2016

Abstract

A system for treating a vascular condition includes a catheter having an inner member and an outer member, the outer member concentrically arranged about the inner member and a retractable drug delivery device disposed at a distal end of the inner member. A coating disposed on at least a portion of an outer surface of the retractable drug delivery device includes at least one therapeutic agent.

First claim

The invention claimed is:

1. A system for treating a vascular condition, the system comprising:
a catheter including an inner member and an outer member, the outer member being concentrically arranged and slideably disposed about the inner member;
a retractable drug delivery device disposed around a distal end of the inner member extending through the retractable drug delivery device, the retractable drug delivery device comprising a plurality of scaffold struts and a plurality of transition struts extending from the plurality of scaffold struts, wherein the scaffold struts of the retractable drug delivery are configured to expand radially from the inner member forming an open passageway wherein the distal end of the scaffold struts are unattached to the inner member;
an attachment, wherein proximal ends of the plurality of transition struts are secured to the attachment and wherein the attachment is formed integrally with the inner member;
a coating disposed on at least a portion of an outer surface of the retractable drug delivery device; and in
at least one therapeutic agent within the coating;
wherein the inner member and the outer member are operable to collapse the retractable drug delivery device from an expanded configuration to a compressed configuration about the inner member within the outer member when the inner member is moved slideably relative to the outer member.

2. The system of claim 1 wherein the transition struts further comprise an arcuate portion.

3. The system of claim 1 wherein the plurality of scaffold struts and the plurality of transition struts comprise a self-expanding material.

4. The system of claim 1 wherein the retractable drug delivery device further comprises a membrane, the membrane having an outer surface for receiving the coating.

5. The system of claim 1 wherein the outer member further comprises a sheath disposed at a distal end of the outer member and covering the retractable drug delivery device when in a delivery configuration.

6. The system of claim 5 wherein the sheath includes a reinforcing material.

7. The system of claim 6 wherein the reinforcing material comprises a metallic material, a polymeric material and combinations thereof.

8. The system of claim 6 wherein the reinforcing material comprises one of a group consisting of a plurality of braided filaments, a plurality of woven filaments, a coil and a helical coil.

9. The system of claim 8 wherein the reinforcing material is disposed between a first polymeric layer and a second polymeric layer.

10. The system of claim 1 wherein the at least one therapeutic agent is selected from a group consisting of anticoagulants, antiinflammatories, fibrinolytics, antiproliferatives, antibiotics, therapeutic proteins, recombinant DNA products, bioactive agents, diagnostic agents, radioactive isotopes, and radiopaque substances.

Assignees

• Cook Brian
• Mitchell James
• Vasquez Natividad
• Pellegrini Gianfranco
• Medtronic Vascular Inc

Inventors

• Cook Brian
• Mitchell James
• Vasquez Natividad
• Pellegrini Gianfranco

Classifications

• A61F2002/9665

  with additional retaining means · CPC title

• A61F2/91

  made from perforated sheets or tubes, e.g. perforated by laser cuts or etched holes · CPC title

• A61M2025/0681

  Systems with catheter and outer tubing, e.g. sheath, sleeve or guide tube · CPC title

• A61M25/0068

  Static characteristics of the catheter tip, e.g. shape, atraumatic tip, curved tip or tip structure · CPC title

• A61F2/95

  Instruments specially adapted for placement or removal of stents or stent-grafts · CPC title