Systems and methods for signal processing in molecular imaging
US-2024013454-A1 · Jan 11, 2024 · US
US9335425B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9335425-B2 |
| Application number | US-201214349103-A |
| Country | US |
| Kind code | B2 |
| Filing date | Oct 12, 2012 |
| Priority date | Oct 12, 2011 |
| Publication date | May 10, 2016 |
| Grant date | May 10, 2016 |
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The invention is directed to several crystal arrangements for time-of-flight (ToF) positron emission tomography (PET) with depth of interaction (DOI) encoding for high spatial, energy and timing resolution. Additionally, several implementations of the ToF-DOI PET detector arrays are proposed with related measurements which all show that no timing degradation is visible in the used setup for first photon trigger for digital silicon photo multipliers (dSiPMs).
Opening claim text (preview).
The invention claimed is: 1. A detector device comprising: a) an assembly with a first layer of scintillation crystals for converting gamma radiation photon energy to light and a second layer of scintillation crystals for converting gamma radiation photon energy to light; b) a first light guide sandwiched between said second layer and said first layer and used for coupling said first and second layers so that the light coming from the second layer is distributed broader than the light originating from the first layer; c) a photo detector array for measuring the light generated in the scintillation crystals, said assembly being mounted with a second light guide onto said photo detector array, said second light guide being sandwiched between said photo detector array and said first layer and used for coupling said first layer and said photo detector array; and d) optical compartments forming a sub-structure of said scintillation crystals and covering side surfaces of said scintillation crystals by a reflective layer. 2. The device according to claim 1 , further comprising light guides structured with at least one of a groove and a composition of a plurality of individual light guides. 3. The device according to claim 1 , wherein the scintillation crystals comprise at least one of a groove and a composition of several individual crystals. 4. The device according to claim 1 , wherein the surfaces of at least one of the light guides and the scintillation crystals are polished or rough, grinded, lapped, omnidirectional or scratched in certain directions on at least one face. 5. The device according to claim 1 , wherein a pitch of said optical compartments is adapted to a sensor die pitch of said photo detector array. 6. The device according to claim 5 , wherein said sensor die pitch of said photo detector array comprises a time-to-digital converter for time stamping. 7. The device according to claim 1 , wherein said optical compartments are adapted to provide reflectors in a first or second direction in said second layer and no reflectors in said first layer, wherein said first direction is perpendicular to said second direction. 8. The device according to claim 1 , wherein said optical compartments are adapted to provide reflectors in a first direction only in said second layer and reflectors in a second direction only in said first layer, or vice versa, wherein said first direction is perpendicular to said second direction. 9. The device according to claim 1 , wherein said optical compartments are square or rectangular at any multiple sensor pitch size or independent from the sensor pitch. 10. The device according to claim 1 , wherein the crystal pitch in said first layer differs from the crystal pitch in said second layer. 11. The device according to claim 1 , wherein the crystal pitch in a crystal layer differs in a first and second direction and wherein said first direction is perpendicular to said second direction. 12. The device according to claim 1 , where the photo detector array is connected to said first layer for readout and said first layer is an inner layer of said detector device. 13. An imaging system for imaging an object, wherein said imaging system comprises a detector device according to claim 1 . 14. A detector device comprising: an assembly with a first layer of scintillation crystals, wherein the first layer of scintillation crystals converts gamma radiation photon energy to light, and a second layer of scintillation crystals, wherein the second layer of scintillation crystals converts gamma radiation photon energy to light; a first light guide sandwiched between said second layer and said first layer, wherein the first light guide couples said first and second layers so that the light coming from the second layer is distributed broader than the light originating from the first layer; a photo detector array, wherein the photo detector array measures the light generated in the scintillation crystals, said assembly being mounted with a second light guide onto said photo detector array, said second light guide being sandwiched between said photo detector array and said first layer, wherein the second light guide couples said first layer and said photo detector array; and optical compartments forming a sub-structure of said scintillation crystals and covering side surfaces of said scintillation crystals by a reflective layer.
Emission tomography · CPC title
In depth localisation, e.g. using positron emitters; Tomographic imaging (longitudinal and transverse section imaging; apparatus for radiation diagnosis sequentially in different planes, steroscopic radiation diagnosis); (using external radiation sources A61B6/02) · CPC title
with scintillation detectors · CPC title
Optical details, e.g. reflecting or diffusing layers · CPC title
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