Test tape cassette and analytical test tape therefor

Patent metadata

Field	Value
Publication number	US-9335333-B2
Application number	US-201414200805-A
Country	US
Kind code	B2
Filing date	Mar 7, 2014
Priority date	Sep 16, 2011
Publication date	May 10, 2016
Grant date	May 10, 2016

Abstract

A test tape cassette is disclosed that includes a cassette housing and an analytical test tape. The test tape includes a plurality of analytical test elements, a spreading fabric for applying a body fluid, and an underlying reagent layer for detecting an analyte in the body fluid. The cassette housing has an application tip that has a guide path extending longitudinally to the test tape in an arched-shape and is uncurved at right angles thereto for supporting the test tape in a kink-free manner. The guide path has an apex area with a central opening that delimits a measuring window for an optical measurement on the test elements.

First claim

The invention claimed is:

1. A test tape cassette for insertion into a hand-held device, the cassette comprising:
a cassette housing for storing at least two tape spools; and
an analytical test tape that can be wound forwards by means of the at least two tape spools, wherein the analytical test tape comprises a plurality of analytical test elements stored thereupon having a spreading fabric and an underlying reagent layer for detecting an analyte of interest,
wherein the cassette housing has an application tip that deflects the analytical test tape to provide at least one of the plurality of test elements, the application tip having a guide path that extends in an arch shape longitudinally to the analytical test tape and is uncurved at right angles thereto for supporting the analytical test tape in a kink-free manner, wherein an apex area of the guide path delimits a central opening as a measuring window for an optical measurement on the at least one of the plurality of test elements,
wherein the test tape when under tension is supported in a planar fashion on the guide path so that the spreading fabric lies gap-free on the underlying reagent layer, and
wherein the application tip comprises a housing wall that is beveled on a rear side towards the measuring window.

2. The test tape cassette of claim 1 , wherein the arch-shaped guide path has a fixed radius of curvature in a range from 3 mm to about 5 mm.

3. The test tape cassette of claim 1 , wherein the guide path has a longitudinal extension in a direction of tape transport in a range from about 5 mm to about 8 mm.

4. The test tape cassette of claim 1 , wherein the guide path has a longitudinal extension in a direction of tape transport that is the same or less than a length of the test elements and is in a range from about 5 mm to about 15 mm.

5. The test tape cassette of claim 1 , wherein the reagent layer, when viewed in a tape transverse direction, is narrower than the analytical test tape and wider than the measuring window.

6. The test tape cassette of claim 1 , wherein the application tip comprises a housing wall that is beveled on a rear side towards the measuring window.

7. The test tape cassette of claim 1 , wherein the application tip is a molded part on the cassette housing and projects from the hand-held device in an operating state to punctually apply a sample fluid.

8. The test cassette of claim 1 , wherein:
the tape has a longitudinal direction and a transverse direction that is transverse to the longitudinal direction; and
the spreading fabric in the longitudinal direction has a bending stiffness that is lower than in the transverse direction.

9. The test cassette of claim 8 , wherein the spreading fabric has one of the thread systems with weakened spots.

10. The test cassette of claim 9 , wherein:
the thread systems include warp threads and weft threads; and
the weft threads have the weakened spots.

11. The test cassette of claim 8 , wherein the spreading fabric has one of the thread systems with thread thicknesses different from the others.

12. The test cassette of claim 11 , wherein:
the thread systems include warp threads and weft threads; and
the warp threads have a lower thread thickness than the weft threads.

13. The test cassette of claim 8 , wherein the bending stiffness is a measure of length of the spreading fabric at which the spreading fabric is bent at a defined angle under the weight of the spreading fabric.

14. A test tape cassette for insertion into a hand-held device, the cassette comprising:
a cassette housing for storing at least two tape spools; and
an analytical test tape that can be wound forwards by means of the at least two tape spools, wherein the analytical test tape comprises a plurality of analytical test elements stored thereupon having a spreading fabric and an underlying reagent layer for detecting an analyte of interest,
wherein the cassette housing has an application tip that deflects the analytical test tape to provide at least one of the plurality of test elements, the application tip having a guide path that extends in an arch shape longitudinally to the analytical test tape and is uncurved at right angles thereto for supporting the analytical test tape in a kink-free manner, wherein an apex area of the guide path delimits a central opening as a measuring window for an optical measurement on the at least one of the plurality of test elements,
wherein the test tape when under tension is supported in a planar fashion on the guide path so that the spreading fabric lies gap-free on the underlying reagent layer, and
wherein the reagent layer, when viewed in a tape transverse direction, is narrower than the analytical test tape and wider than the measuring window.

15. A test tape cassette, comprising:
an analytical test tape having a longitudinal direction and a transverse direction that is transverse to the longitudinal direction, wherein the test tape includes
a transport tape, and
a plurality of analytical test elements stored on the transport tape, wherein the test elements are spaced apart from one another in the longitudinal direction of the test tape, wherein the test elements each include
a reagent layer to detect analyte, and
a spreading fabric covering the reagent layer;

an application tip having a guide path around which the test tape is bent, wherein the guide path is convex relative to the test tape in the longitudinal direction and flat in the transverse direction; and
wherein the spreading fabric in the longitudinal direction has a bending stiffness that is lower than in the transverse direction.

16. The test cassette of claim 15 , wherein the spreading fabric has a thread system with weakened spots.

17. The test cassette of claim 16 , wherein:
the thread system includes warp threads and weft threads; and
the weft threads have the weakened spots.

18. The test cassette of claim 15 , wherein the spreading fabric has a thread system with thread thicknesses different from the others.

19. The test cassette of claim 18 , wherein:
the thread system includes warp threads and weft threads; and
the warp threads have a lower thread thickness than the weft threads.

20. The test cassette of claim 15 , wherein the bending stiffness is a measure of length of the spreading fabric at which the spreading fabric is bent at a defined angle under the weight of the spreading fabric.

Assignees

• Roche Diabetes Care Inc

Inventors

• Dreibholz Joerg
• Freitag Christian
• Jaeck Thomas
• Keth Ingrid
• Pachl Rudolf
• Schmidtchen Elke
• Schwoebel Wolfgang
• Seelig Peter

Classifications

• G01N2035/00019

  cassette structures · CPC title

• G01N33/48764

  Test tape taken off a spool · CPC title

• G01N35/00009 Primary

  provided with a sample supporting tape, e.g. with absorbent zones · CPC title

• G01N21/8483 Primary

  Investigating reagent band (test-element handling not specific to a test method G01N33/4875; analytical elements specific to chemical analysis of biological material G01N33/52; autometer with reagent band G01N35/04) · CPC title

• G01N35/00

  Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor · CPC title