Guerbet alcohol mixtures and uses thereof

Patent metadata

Field	Value
Publication number	US-9333262-B2
Application number	US-201313768264-A
Country	US
Kind code	B2
Filing date	Feb 15, 2013
Priority date	Feb 17, 2012
Publication date	May 10, 2016
Grant date	May 10, 2016

Abstract

Mixtures of Guerbet alcohols, their use in cosmetic and/or pharmaceutical preparations, and also cosmetic and/or pharmaceutical preparations comprising mixtures of Guerbet alcohols are described. Of suitability as petroleum jelly substitute are in particular Guerbet alcohol mixtures with a melting range, measured by differential scanning calorimetry (DSC), between −20° C. and +70° C., where the width of the melting range comprises at least 30 temperature degrees and the maximum of the melting range is 35±10° C. These are obtainable for example by reacting
a) 55 to 95% by weight of cetylstearyl alcohol, b) 5 to 45% by weight of fatty alcohols with a chain length of from 8 to 22 carbon atoms and c) optionally an aliphatic diol having at least 3 carbon atoms.

First claim

What is claimed is:

1. A Guerbet alcohol mixture obtainable by reacting:
a) 55 to 70% by weight of cetylstearyl alcohol; with
b) 5 to 40% by weight of fatty alcohols with a chain length of 8 to 22 carbon atoms; and
c) 5% by weight of an aliphatic diol having at least 3 carbon atoms,
with the proviso that the mixture has a melting range, measured by differential scanning calorimetry (DSC), between −20° C. and +70° C., where the width of the melting range comprises at least 30 temperature degrees and the maximum of the melting range is 35±15° C.

2. The Guerbet alcohol mixture of claim 1 , wherein the Guerbet alcohol mixture has a melting range between −10° C. and +60° C., where the width of the melting range comprises at least 40 temperature degrees and the maximum of the melting range is 35±10° C.

3. The Guerbet alcohol mixture of claim 1 , wherein the component a) consists of unbranched fatty alcohols with a chain distribution of
C16 of 45-55%, and
C18 of 45-55%.

4. The Guerbet alcohol mixture of claim 1 , wherein the component b) consists essentially of fatty alcohols with a chain length of from 12 to 18 carbon atoms.

5. The Guerbet alcohol mixture of claim 1 , wherein the component b) consists of unbranched, saturated fatty alcohols having the following chain distribution:
C12 from 48-58% by weight
C14 from 18-24% by weight
C16 from 8-12% by weight
C18 from 11-15% by weight.

6. The Guerbet alcohol mixture of claim 1 , wherein component c) comprises hexanediol.

7. The Guerbet alcohol mixture of claim 1 , wherein the Guerbet reaction is carried out at temperatures of from 200 to 260° C.

8. The Guerbet alcohol mixture of claim 1 , wherein the Guerbet reaction is operated until 60-80% of the conversion of the starting alcohols has been achieved.

9. A cosmetic and/or pharmaceutical preparation comprising the Guerbet alcohol mixture of claim 1 .

Assignees

• Basf Se

Inventors

• Kempers Peter
• Kawa Rolf
• Brüning Stefan
• Milardovic Jadranka
• Mahnke Eike Ulf
• Krüppel Heinz-Josef
• Dierker Markus
• Beckedahl Burkhard

Classifications

• A61Q19/00

  Preparations for care of the skin · CPC title

• A61K47/10 Primary

  Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers · CPC title

• A61K8/345

  containing more than one hydroxy group · CPC title

• A61K2800/10

  General cosmetic use · CPC title