Line-field holoscopy

Patent metadata

Field	Value
Publication number	US-9332902-B2
Application number	US-201313745632-A
Country	US
Kind code	B2
Filing date	Jan 18, 2013
Priority date	Jan 20, 2012
Publication date	May 10, 2016
Grant date	May 10, 2016

Abstract

A novel imaging method, line-field holoscopy is presented. A line of light is projected across an object to be investigated through an imaging system. The light scattered from the investigated object is combined with reference radiation. The combined light is projected onto a detector providing a confocal restriction in one dimension. Astigmatic optics in the return path transform the light asymmetrically such that at the detector, the line focus is imaged to the confocal restriction, while the orthogonal direction is defocused. Embodiments including a swept source with linear detection array, and spectrometer based systems utilizing a 2D detector array are described. The data may be reconstructed to a B-scan by two-dimensional Fourier transform or other reconstruction method with or without combination of more complex algorithms.

First claim

What is claimed is:

1. An interferometric imaging device for imaging a light scattering object comprising:
a broadband light source arranged to generate a beam of radiation that is swept in frequency;
a beam divider for separating the beam into reference and sample arms, wherein the sample arm contains the light scattering object to be imaged;
optics to focus said beam of radiation to a line focus on the light scattering object to be imaged, said line focus having a long axis and a narrow axis;
collection optics for combining light scattered from the object and light returning from the reference arm, said collection optics also including an astigmatic element for focusing the light along the long axis differently than along the narrow axis;
a one dimensional sensor array arranged such that the narrow dimension of the line focus is substantially imaged directly to the narrow axis of the sensor array and such that the line focus is defocused along its long axis on the sensor array; and
a processor for generating an image in response to signals generated by the detector.

2. A device as recited in claim 1 , wherein the long axis of the line focus is defocused by at least one Rayleigh length on the sensor array.

3. An interferometric imaging device as recited in claim 2 , wherein an angle is introduced between the sample and reference light such that a phase ramp is introduced across the long axis of the detector.

4. An interferometric imaging device as recited in claim 1 , wherein the scattering object is a retina of an eye.

5. A device as recited in claim 1 , wherein the generation of the image by the processor includes reconstructing the output from the detector to transfer between optical frequency and angular direction to the spatial distribution of scattering in the object, wherein the optical frequency encodes the axial spatial frequency and the angular direction encodes the lateral spatial frequency.

6. A device as recited in claim 5 , wherein the generation of the image by the processor includes performing a two-dimensional Fourier transformation of axial spatial frequency and lateral spatial frequency to create a spatial distribution of scattering in the object.

7. An interferometric imaging device for imaging a light scattering object comprising:
a light source arranged to generate a beam of radiation;
a beam divider for separating the beam into reference and sample arms, wherein the sample arm contains the light scattering object to be imaged;
optics to focus said beam of radiation to a line focus on the light scattering object to be imaged, said line focus having a long axis and a narrow axis;
a detector array;
collection optics for combining light scattered from the object and light from the reference arm and directing the combined light to the detector; and
a processor for generating an image in response to signals generated by the detector, wherein digital refocusing is used to obtain high lateral resolution at depths outside of the focused region and wherein the detector array is a one dimensional sensor array arranged such that the narrow dimension of the line focus is substantially imaged directly to the narrow axis of the sensor array and such that the line focus is defocused along its long axis on the sensor array.

8. An interferometric imaging device as recited in claim 7 , wherein the collection optics include an astigmatic optic.

9. An interferometric imaging device as recited in claim 7 , wherein an angle is introduced between the sample and reference light such that a phase ramp is introduced across the long axis of the detector.

10. An interferometric imaging device as recited in claim 7 , wherein the light source is swept in optical frequency.

11. An interferometric imaging device as recited in claim 7 , wherein the light source is an SLD.

12. An interferometric imaging device as recited in claim 7 , wherein the scattering object is a retina of an eye.

13. An interferometric imaging device as recited in claim 7 , wherein the digital refocusing includes reconstructing the output from the detector to transfer between optical frequency and angular direction to the spatial distribution of scattering in the object, wherein the optical frequency encodes the axial spatial frequency and the angular direction encodes the lateral spatial frequency.

14. An interferometric imaging device as recited in claim 7 wherein the digital refocusing is achieved by performing a digital wavefront propagation on the output from the detector to create axial and lateral spatial distributions of scattering in the object.

Assignees

• Zeiss Carl Meditec Inc

Inventors

• Tumlinson Alexandre R
• Everett Matthew J

Classifications

• G01B9/02043

  Imaging of the Fourier or pupil or back focal plane, i.e. angle resolved imaging · CPC title

• G01B9/02047

  using digital holographic imaging, e.g. lensless phase imaging without hologram in the reference path · CPC title

• G01B9/02044

  Imaging in the frequency domain, e.g. by using a spectrometer · CPC title

• G01B9/02091

  Tomographic interferometers, e.g. based on optical coherence · CPC title

• A61B3/102 Primary

  for optical coherence tomography [OCT] · CPC title