Protection from hydrophobizing agents

Patent metadata

Field	Value
Publication number	US-9329164-B2
Application number	US-201213446656-A
Country	US
Kind code	B2
Filing date	Apr 13, 2012
Priority date	Oct 15, 2009
Publication date	May 3, 2016
Grant date	May 3, 2016

Abstract

The present invention concerns storage containers for storing diagnostic elements having a hydrophilic or hydrophilically coated surface. Furthermore, the invention concerns analytical measuring devices which comprise storage containers of this type, and the use of an absorption material for selectively absorbing hydrophobic, volatile substances in such storage containers.

First claim

What is claimed is:

1. A storage container, comprising:
a housing;
at least one diagnostic element configured to detect an analyte contained in a body liquid, the diagnostic element disposed in the housing and having a hydrophilic surface or a hydrophilically coated surface;
at least one porous absorption material for selectively absorbing at least one hydrophobic, volatile substance, wherein the housing is formed at least partially of a material comprising at least one hydrophobic, volatile substance, wherein said material is selected from plastics and paper; and
wherein the at least one porous absorption material comprises a mixture of a first porous absorption material defining a first pore size and a second porous absorption material defining a second pore size, the first pore size being approximately 0.56 nm and the second pore size being approximately 0.76.

2. The storage container of claim 1 , wherein the at least one absorption material is a naturally occurring or synthetic silicate.

3. The storage container of claim 1 , wherein the at least one absorption material comprises zeolite.

4. The storage container of claim 1 , wherein the at least one absorption material comprises an absorber element that is separate from and provided in the housing.

5. The storage container of claim 1 , wherein the at least one absorption material is integrated into the housing.

6. The storage container of claim 1 , wherein the at least one diagnostic element comprises a sample collection element that is integrated into the housing.

7. The storage container of claim 6 , wherein the sample collection element comprises a needle element having a capillary channel.

8. The storage container of claim 1 , wherein the at least one diagnostic element comprises a sample collection element having a capillary channel.

9. The storage container of claim 8 , wherein the sample collection element comprises a needle element.

10. The storage container of claim 8 , wherein the sample collection element comprises a hydrophilic coating of one or more of polyacrylic acid, polyacrylate, dextran sulfate, heparin, lecithin and detergent.

11. The storage container of claim 10 , wherein the sample collection element forms a contact angle of ≦40° with a drop of water applied to the hydrophilic coating after storage for 9 weeks at a temperature of 35° C.

12. The storage container of claim 10 , wherein the sample collection element forms a contact angle of ≦25° with a drop of water applied to the hydrophilic coating after storage for 9 weeks at a temperature of 35° C.

13. The storage container of claim 1 , wherein the at least one diagnostic element comprises a test tape or a test strip.

14. The storage container of claim 1 , wherein the at least one diagnostic element is sterile-packed.

15. The storage container of claim 1 , wherein the storage container does not further comprise a desiccant.

16. The storage container of claim 1 , wherein the housing comprises a plastic derived from polyamide, polycarbonate, polyester, polyethylene or polypropylene.

17. The storage container of claim 1 , wherein the container comprises a blister magazine, leporello magazine, disk magazine, stack magazine or drum magazine.

18. An analytical measuring device comprising a storage container according to claim 1 .

19. A storage container, comprising:
a housing;
at least one diagnostic element configured to detect an analyte contained in a body liquid, the diagnostic element disposed in the housing and having a hydrophilic surface or a hydrophilically coated surface;
at least one absorption material for selectively absorbing at least one hydrophobic, volatile substance, wherein the absorption material has pores with a diameter of at least 0.5 nm; and
wherein the at least one porous absorption material comprises a mixture of a first porous absorption material defining a first pore size and a second porous absorption material defining a second pore size, the first pore size being approximately 0.56 nm and the second pore size being approximately 0.76 nm.

20. A storage container, comprising:
a housing;
at least one diagnostic element configured to detect an analyte contained in a body liquid, the diagnostic element disposed in the housing and having a hydrophilic surface or a hydrophilically coated surface;
at least one porous absorption material for selectively absorbing at least one hydrophobic, volatile substance having a molecular weight of 100 to 1000 Daltons; and
wherein the at least one porous absorption material comprises a mixture of a first porous absorption material defining a first pore size and a second porous absorption material defining a second pore size, the first pore size being approximately 0.56 nm and the second pore size being approximately 0.76 nm.

21. A storage container, comprising:
a housing;
at least one diagnostic element configured to detect an analyte contained in a body liquid wherein the analyte is selected from the group consisting of malic acid, alcohol, ammonium, ascorbic acid, cholesterol, cysteine, glucose, glutathione, glycerol, urea, 3-hydroxybutyrate, lactic acid, 5′-nucleotidase, peptides, pyruvate, salicylate and triglycerides; the diagnostic element disposed in the housing and having a hydrophilic surface or a hydrophilically coated surface;
at least one porous absorption material for selectively absorbing at least one hydrophobic, volatile substance, wherein the housing is formed at least partially of a material comprising at least one hydrophobic, volatile substance, wherein said material is selected from plastics and paper; and
wherein the at least one porous absorption material comprises a mixture of a first porous absorption material defining a first pore size and a second porous absorption material defining a second pore size, the first pore size being approximately 0.56 nm and the second pore size being approximately 0.76 nm.

22. A storage container, comprising:
a housing;
at least one diagnostic element configured to detect an analyte contained in a body liquid wherein the analyte is selected from the group consisting of malic acid, alcohol, ammonium, ascorbic acid, cholesterol, cysteine, glucose, glutathione, glycerol, urea, 3-hydroxybutyrate, lactic acid, 5′-nucleotidase, peptides, pyruvate, salicylate and triglycerides; the diagnostic element disposed in the housing and having a hydrophilic surface or a hydrophilically coated surface;
at least one absorption material for selectively absorbing at least one hydrophobic, volatile substance, wherein the absorption material has pores with a diameter of at least 0.5 nm; and
wherein the at least one porous absorption material comprises a mixture of a first porous absorption material defining a first pore size and a second porous absorption material defining a second pore size, the first pore size being approximately 0.56 nm and the second pore size being approximately 0.76 nm.

23. A storage container, comprising:
a housing;
at least one diagnostic element configured to detect an analyte contained in a body liquid wherein the analyte is selected from the group consisting of malic acid, alcohol, ammonium, ascorbic acid, cholesterol, cysteine, glucose, glutathione, glycerol, urea, 3-hydroxybutyrate, lactic acid, 5′-nucleotidase, peptides, pyruvate, salicylate and triglycerides; the diagnostic element disposed in the housing and having a hydrophilic surface or a hydrophilically coated surface;
at least one porous

Assignees

• Babic Bransilav
• Leichner Wilhelm
• Roche Diabetes Care Inc

Inventors

• Babic Bransilav
• Leichner Wilhelm

Classifications

• G01N33/48778 Primary

  Containers specially adapted therefor, e.g. for dry storage · CPC title

• B01L2300/0825

  Test strips · CPC title

• B65D81/266

  for absorbing gases, e.g. oxygen absorbers or desiccants (B65D51/244, B65D51/30 take precedence) · CPC title

• B01L3/5027

  by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip · CPC title

• B01L2400/0406

  capillary forces · CPC title