Medicament delivery device

Patent metadata

Field	Value
Publication number	US-9327083-B2
Application number	US-201113639797-A
Country	US
Kind code	B2
Filing date	Apr 5, 2011
Priority date	Apr 7, 2010
Publication date	May 3, 2016
Grant date	May 3, 2016

Abstract

Provided is a medicament delivery device ( 100 ) comprising a tubular housing ( 110 ), having a proximal end ( 111 ) and an opposite distal end ( 112 ), an actuator means ( 119, 120 ), slidably and coaxially arranged inside the tubular housing ( 110 ) wherein is provided an inter-locking mechanism ( 119, 413 ) between the a cap ( 410 ) and the housing ( 110 ), enabling the cap ( 410 ) to freely spin, i.e. it is impossible to open the cap ( 410 ), until the medicament delivery device ( 100 ) has been properly activated by an activator means ( 160 ).

First claim

The invention claimed is:

1. A medicament delivery device comprising:
a tubular housing having a proximal end and an opposite distal end;
an actuator slidably and coaxially arranged inside the tubular housing and comprising a proximal annular contact member;
a first resilient member arranged at a distal end of the actuator between an annular ledge of the tubular housing and an annular ledge of the actuator;
a medicament container holder coaxially arranged within the actuator and fixedly attached to the tubular housing, wherein the medicament container holder further comprises a medicament container having a medicament therein, the medicament container further housing at least one slidable stopper and a membrane;
an activating member interactively connected to the actuator and configured for holding the actuator and the first resilient member in a pre-tensioned state;
a driver interactively connected either to the actuator or to the actuator and the activating member for driving the slidable stopper;
a delivery member, comprising a retainer member fixedly connected to the container holder, a hub coaxially movable within the retainer member and having a needle having a proximal and an opposite distal end, an inner cap interactively connected to the hub and to the retainer member, and an outer cap coaxially arranged to the inner cap, wherein the outer cap is rotatably spinning in relation to the inner cap when the actuator and the first resilient member are in the pre-tensioned state; and
a cap inter-locking member axially slidable and rotationally locked to the inner cap and abutting the proximal annular contact member, wherein the cap inter-locking member is configured for interacting with the outer cap when the actuator and the first resilient member are released from the pre-tensioned state;
wherein the actuator comprises a tubular activation member and an intermediate longitudinal locking member; the proximal annular contact member is coaxially arranged within an inner surface proximal end of the tubular activation member; the intermediate longitudinal locking member further comprises a first co-acting device interactively connected to a corresponding first co-acting device of the activating member for holding the actuator and the first resilient member in the pre-tensioned state; the first co-acting device is a radial, outwardly extending protrusion; and the corresponding first co-acting device of the activating member is a radial inwardly extending protrusion.

2. The medicament delivery device of claim 1 , wherein the driver comprises a tubular operation member having an inner co-acting device on its inner surface and an outer co-acting device on its outer surface, a plunger rod, a second resilient member pre-tensionedly arranged within the plunger rod, and a plunger rod support member.

3. The medicament delivery device of claim 2 , wherein the intermediate longitudinal locking member further comprises a second co-acting device interactively connected to the outer co-acting device of the tubular operation member.

4. The medicament delivery device of claim 3 , wherein the second co-acting device is a radial inwardly extending protrusion and the outer co-acting device of the tubular operation member is a groove-track.

5. The medicament delivery device of claim 4 , wherein the plunger rod comprises a third co-acting device firstly releasably connected to an inner co-acting device of the activating member and releasably connected to the inner co-acting device of the tubular operation member when the medicament container is a dual chamber cartridge, such that when the activating member is manually operated, the plunger rod is released from the activating member and moves proximally by a force of the second resilient member such that the plunger rod exerts a pressure on the slidable stopper for performing a mixing of medicament, until the third co-acting device abuts the inner co-acting device of the tubular operation member, and when the actuator is pressed against a delivery site, the tubular operation member is rotated, whereby the plunger rod is released from the tubular operation member and driven proximally by a force of the second resilient member such that the plunger rod exerts a pressure on the slidable stopper and the medicament is expelled through the delivery member.

6. The medicament delivery device of claim 1 , wherein the cap inter-locking member is an intermediate annular member, having a co-acting device adapted to engage with a corresponding annular co-acting device on an inner sheath of the outer cap, enabling rotation of the outer cap.

7. The medicament delivery device of claim 1 , wherein the driver comprises a tubular operation member having an inner co-acting device on its inner surface and an outer co-acting device on its outer surface, a plunger rod, a second resilient member pre-tensionedly arranged within the plunger rod, and a plunger rod support member.

8. A medicament delivery device comprising:
a tubular housing having a proximal end and an opposite distal end;
an actuator slidably and coaxially arranged inside the tubular housing and comprising a proximal annular contact member;
a first resilient member arranged at a distal end of the actuator between an annular ledge of the tubular housing and an annular ledge of the actuator;
a medicament container holder coaxially arranged within the actuator and fixedly attached to the tubular housing;
an activating member interactively connected to the actuator and configured for holding the actuator and the first resilient member in a pre-tensioned state;
a delivery member, comprising a retainer member fixedly connected to the container holder, a hub coaxially movable within the retainer member and having a needle having a proximal and an opposite distal end, an inner cap interactively connected to the hub and to the retainer member, and an outer cap coaxially arranged to the inner cap, wherein the outer cap is rotatably spinning in relation to the inner cap when the actuator and the first resilient member are in the pre-tensioned state;
a cap inter-locking member axially slidable and rotationally locked to the inner cap and abutting the proximal annular contact member, wherein the cap inter-locking member is configured for interacting with the outer cap when the actuator and the first resilient member are released from the pre-tensioned state; and
a driver interactively connected either to the actuator or to the actuator and the activating member for driving the slidable stopper;
wherein the medicament container holder further comprises a medicament container having a medicament therein, the medicament container further housing at least one slidable stopper and a membrane; the actuator comprises a tubular activation member and an intermediate longitudinal locking member; the proximal annular contact member is coaxially arranged within an inner surface proximal end of the tubular activation member; the intermediate longitudinal locking member further comprises a first co-acting device interactively connected to a corresponding first co-acting device of the activating member for holding the actuator and the first resilient member in the pre-tensioned state; the driver comprises a tubular operation member having an inner co-acting device on its inner surface and an outer co-acting device on its outer surface, a plunger rod, a second resilient member pre-tensionedly arranged within the plunger rod, and a plunger rod support member; the intermediate longitudinal locking member further comprises a second co-acting device interactively connected to the outer co-acting device of the tubular operation member; the plunger rod comprises a third co-acting device releasably connected to the inner c

Assignees

• Giambattista Lucio
• Bendek Antonio
• Shl Group Ab

Inventors

• Giambattista Lucio
• Bendek Antonio

Classifications

• A61M5/3156

  using volume steps only adjustable in discrete intervals, i.e. individually distinct intervals · CPC title

• A61M5/3202 Primary

  Devices for protection of the needle before use, e.g. caps (A61M5/50 takes precedence; for infusion spikes A61M5/1626; protectors for sharps A61B50/3001) · CPC title

• A61M2205/586

  Ergonomic details therefor, e.g. specific ergonomics for left or right-handed users · CPC title

• A61M2005/2073

  preventing premature release, e.g. by making use of a safety lock · CPC title

• A61M5/2448 Primary

  comprising means for injection of two or more media, e.g. by mixing · CPC title