Inhibitors of tyk2
US-2024425484-A1 · Dec 26, 2024 · US
US9326987B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9326987-B2 |
| Application number | US-201113821594-A |
| Country | US |
| Kind code | B2 |
| Filing date | Sep 6, 2011 |
| Priority date | Sep 8, 2010 |
| Publication date | May 3, 2016 |
| Grant date | May 3, 2016 |
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The present invention is directed to compounds for use in the treatment or prevention of influenza virus infection.
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What is claimed is: 1. A method of ameliorating symptoms of influenza virus infection comprising administering a safe and effective amount of the compound N-[5-[4-(5-{[(2R,6S)-2,6-dimethyl-4-morpholinyl]methyl}-1,3-oxazol-2-yl)-1H-indazol-6-yl]-2-(methyloxy)-3-pyridinyl]methanesulfonamide; or a pharmaceutically acceptable salt thereof. 2. A method of ameliorating symptoms of influenza virus infection comprising administering a safe and effective amount of the compound 6-(1H-indol-4-yl)-4-(5-{[4-(1-methylethyl)-1-piperazinyl]methyl}-1,3-oxazol-2-yl)-1H-indazole; or a pharmaceutically acceptable salt thereof. 3. A method of ameliorating symptoms of influenza virus infection comprising administering a safe and effective amount of the compound 6-(1H-indol-4-yl)-4-(5-{[4-(1-methylethyl)-1-piperazinyl]methyl}-1,3-oxazol-2-yl)-1H-indazole hemi succinate.
not condensed and containing further heterocyclic rings · CPC title
spiro-condensed or forming part of bridged ring systems · CPC title
Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin · CPC title
Oxadiazoles · CPC title
containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole (nicotine A61K31/465) · CPC title
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