Bioabsorbable polymeric compositions, processing methods, and medical devices therefrom

Patent metadata

Field	Value
Publication number	US-9321917-B2
Application number	US-201514886590-A
Country	US
Kind code	B2
Filing date	Oct 19, 2015
Priority date	Sep 22, 2010
Publication date	Apr 26, 2016
Grant date	Apr 26, 2016

Abstract

Novel bioabsorbable polymeric blends are disclosed. The blends have a first component that is a polylactide polymer or a copolymer of lactide and glycolide and a second component that is poly(p-dioxanone) polymer. The novel polymeric blends provide medical devices having dimensional stability. Also disclosed are novel bioabsorbable medical devices made from these novel polymer blends, as well as novel methods of manufacture.

First claim

We claim:

1. A bioabsorbable melt polymer blend, comprising:
82 weight percent to 88 weight percent of a first bioabsorbable polymer and 12 weight percent to 18 weight percent of a second bioabsorbable polymer, the first bioabsorbable polymer comprising a lactide-rich polymer comprising about 95 mol percent to about 75 mol percent polymerized lactide and about 5 mol percent to about 25 mol percent polymerized glycolide, and the second bioabsorbable polymer comprising poly(p-dioxanone),
wherein the polymer blend has a maximum weight percent of poly(p-dioxanone) of 18 weight percent and a minimum weight percent of poly(p-dioxanone) that depends upon the molar amount of polymerized lactide in the lactide-rich polymer and is calculated by the expression:
Weight Percent Poly(p-dioxanone)=(215.6212/Mol Percent Polymerized Lactide) 2.7027

and wherein the polymer blend provides dimensional stability to a manufactured article.

Assignees

• Ethicon Inc

Inventors

• Kelly Brian M
• Jamiolkowski Dennis D
• Defelice Christopher

Classifications

• A61L2300/404

  Biocides, antimicrobial agents, antiseptic agents · CPC title

• A61B2017/0647

  having one single leg, e.g. tacks · CPC title

• A61B17/0401

  Suture anchors, buttons or pledgets, i.e. means for attaching sutures to bone, cartilage or soft tissue; Instruments for applying or removing suture anchors (A61B17/0642 takes precedence; fixation devices for tendons or ligaments A61F2/0811) · CPC title

• A61L2300/442

  Colorants, dyes · CPC title

• A61L31/041 Primary

  Mixtures of macromolecular compounds · CPC title