Sensing chip, sensing chip manufacturing method, sensing kit, measuring method and measuring device
US-2024319093-A1 · Sep 26, 2024 · US
Method and apparatus for optical sensing using an optical sensor including a leaky mode waveguide
US9316579B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9316579-B2 |
| Application number | US-201013509502-A |
| Country | US |
| Kind code | B2 |
| Filing date | Nov 10, 2010 |
| Priority date | Nov 11, 2009 |
| Publication date | Apr 19, 2016 |
| Grant date | Apr 19, 2016 |
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- Title
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Abstract
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An optical sensor comprising a waveguide having a sensing layer which is molecularly imprinted such that it will receive and retain target entities to be sensed, the optical sensor further comprising a detection apparatus arranged to detect a change of an optical property of the waveguide which occurs when the target entities are received and retained in the sensing layer.
First claim
Opening claim text (preview).
The invention claimed is: 1. An optical sensor comprising a leaky mode waveguide having a sensing layer which is molecularly imprinted such that it will receive and retain target entities to be sensed, the optical sensor further comprising a detection apparatus arranged to detect a change of an optical property of the leaky mode waveguide which occurs when the target entities are received and retained in the sensing layer, and wherein the optical sensor forms part of a contamination detector which is part of a purification system. 2. An optical sensor as claimed in claim 1 , wherein the sensing layer comprises reception sites having shapes which are suitable for receiving the target entities. 3. An optical sensor as claimed in claim 1 , wherein the sensing layer comprises reception sites having functional groups which are complementary to functional groups of the target entities. 4. An optical sensor as claimed in claim 1 , wherein the sensing layer is porous. 5. An optical sensor as claimed in claim 1 , wherein the target entities are ribonuclease. 6. An optical sensor as claimed in claim 1 , wherein the target entities are inactive. 7. An optical sensor as claimed in claim 1 , wherein the leaky mode waveguide includes a layer of material having a refractive index which is higher than the refractive index of the sensing layer. 8. An optical sensor as claimed in claim 7 , wherein the layer of material is a metal layer. 9. An optical sensor as claimed in claim 1 , wherein the sensing layer is a polymer layer.
Assignees
Inventors
Classifications
involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings · CPC title
Index · CPC title
Assays involving molecular imprinted polymers/polymers created around a molecular template · CPC title
- G01N21/553Primary
and using surface plasmons (fluorescence excitation G01N21/648; enhanced Raman G01N21/658) · CPC title
using reagent-clad optical fibres or optical waveguides (using measurement of total internal reflection or attenuated total reflection G01N21/552; optical fibres or waveguides per se G02B) · CPC title
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- What does patent US9316579B2 cover?
- An optical sensor comprising a waveguide having a sensing layer which is molecularly imprinted such that it will receive and retain target entities to be sensed, the optical sensor further comprising a detection apparatus arranged to detect a change of an optical property of the waveguide which occurs when the target entities are received and retained in the sensing layer.
- Who is the assignee on this patent?
- Goddard Nicholas John, Taylor Paul, Emd Millipore Corp
- What technology area does this patent fall under?
- Primary CPC classification G01N21/553. Mapped technology areas include Physics.
- When was this patent published?
- Publication date Tue Apr 19 2016 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).