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Methods and materials for prolonging useful storage of red blood cell preparations and platelet preparations
US9315775B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9315775-B2 |
| Application number | US-201414307698-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jun 18, 2014 |
| Priority date | Mar 16, 2011 |
| Publication date | Apr 19, 2016 |
| Grant date | Apr 19, 2016 |
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Abstract
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This document provides methods and materials for enhancing the storage capabilities of red blood cell preparations. For example, methods and materials for using CO 2 to store red blood cells in a manner that (a) reduces the level of glucose or 2,3-DPG consumption of or reduces the level of 2,3-DPG production by a red blood cell preparation, (b) reduces the level of lactate formation by a red blood cell preparation, and/or (c) reduces the pH level of a red blood cell preparation are provided. Such methods and materials can result in prolonging the useful lifespan of the red blood cells of the red blood cell preparation. This document also provides methods and materials involved in prolonging useful storage of platelet preparations. For example, methods and materials for storing platelets in a manner that reduces platelet metabolism, that preserves platelet function, and/or that reduces the risk of bacterial contamination are provided.
First claim
Opening claim text (preview).
What is claimed is: 1. A method for treating a platelet concentrate, the method comprising: exposing a platelet concentrate to CO 2 gas under conditions wherein the pCO 2 level of said platelet concentrate is about 150 mmHg of pCO 2 to about 600 mmHg of pCO 2 . 2. The method of claim 1 , wherein said method comprises exposing said platelet concentrate to CO 2 gas under conditions wherein the pCO 2 level of said platelet concentrate is about 200 to about…
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Human Necessities · mapped topic
- A01N1/126Primary
Human Necessities · mapped topic
- A01N1/10Primary
Human Necessities · mapped topic
Human Necessities · mapped topic
- C12N5/0644Primary
Chemistry & Metallurgy · mapped topic
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- What does patent US9315775B2 cover?
- This document provides methods and materials for enhancing the storage capabilities of red blood cell preparations. For example, methods and materials for using CO 2 to store red blood cells in a manner that (a) reduces the level of glucose or 2,3-DPG consumption of or reduces the level of 2,3-DPG production by a red blood cell preparation, (b) reduces the level of lactate formation by a red b…
- Who is the assignee on this patent?
- Mayo Foundation, Dynasil Biomedical Corp
- What technology area does this patent fall under?
- Primary CPC classification A01N1/126. Mapped technology areas include Human Necessities.
- When was this patent published?
- Publication date Tue Apr 19 2016 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).