Nitrogen-containing heterocyclic compound
US-2015307497-A1 · Oct 29, 2015 · US
US9315458B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9315458-B2 |
| Application number | US-201514693342-A |
| Country | US |
| Kind code | B2 |
| Filing date | Apr 22, 2015 |
| Priority date | Apr 23, 2014 |
| Publication date | Apr 19, 2016 |
| Grant date | Apr 19, 2016 |
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The present invention provides a compound having a cholinergic muscarinic M1 receptor positive allosteric modulator activity and useful as an agent for the prophylaxis or treatment of Alzheimer's disease, schizophrenia, pain, sleep disorder, Parkinson's disease dementia, dementia with Lewy bodies, and the like. The present invention relates to a compound represented by the formula (I) or a salt thereof. wherein each symbol is as described in the specification, or a salt thereof.
Opening claim text (preview).
The invention claimed is: 1. 4-Fluoro-2-[(3S,4S)-4-hydroxytetrahydro-2H-pyran-3-yl]-5-methyl-6-[4-(1H-pyrazol-1-yl)benzyl]-2,3-dihydro-1H-isoindol-1-one, or a salt thereof. 2. A medicament comprising 4-Fluoro-2-[(3S,4S)-4-hydroxytetrahydro-2H-pyran-3-yl]-5-methyl-6-[4-(1H-pyrazol-1-yl)benzyl]-2,3-dihydro-1H-isoindol-1-one or a salt thereof, and a pharmaceutically acceptable carrier.
Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00 · CPC title
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Hypnotics; Sedatives · CPC title
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Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] · CPC title
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