Liquid cation exchanger

Patent metadata

Field	Value
Publication number	US-9315443-B2
Application number	US-201114000067-A
Country	US
Kind code	B2
Filing date	Dec 1, 2011
Priority date	Feb 16, 2011
Publication date	Apr 19, 2016
Grant date	Apr 19, 2016

Abstract

The invention relates to a method for removing an organic compound having one or more positive charges from an aqueous solution. Said method consists of the following steps a) the aqueous solution containing the organic compound, and a hydrophobic organic solution which contains a hydrophobic liquid cation exchanger having one or more negative charges and a negative total charge, are provided, b) the aqueous solution and the organic solution are brought into contact with each other and c) the organic solution is separated from the aqueous solution.

First claim

The invention claimed is:

1. A method for removing an organic compound from an aqueous solution, the method comprising:
a) contacting an aqueous solution comprising an organic compound with a hydrophobic organic solution comprising a hydrophobic liquid cation exchanger, and
b) separating the organic solution from the aqueous solution,
wherein the organic compound has a formula I
NH 3 + -A-COOR 1   (I),

wherein R 1 is hydrogen, methyl, ethyl or a negative charge and A is an unsubstituted, linear alkylene group comprising at least three carbon atoms,
wherein the liquid cation exchanger is a fatty acid, and
wherein the contacting is performed at a temperature of 28 to 70° C.

2. The method of claim 1 , wherein the contacting is performed at a pH of 6 to 8.

3. The method of claim 1 , wherein a molar ratio of the liquid cation exchanger to the organic compound is at least 1.

4. The method of claim 1 , wherein a volume ratio of the organic solution to the aqueous solution is 1:10 to 10:1.

5. The method of claim 1 , wherein the liquid cation exchanger is a fatty acid comprising more than 12 carbon atoms.

6. The method of claim 1 , wherein the liquid cation exchanger is an unsaturated fatty acid.

7. The method of claim 1 , wherein the aqueous solution further comprises a biological catalyst agent having catalytic activity.

8. The method of claim 7 , wherein the biological agent is a cell.

9. The method of claim 7 , wherein the presence of the organic compound has an adverse effect on the catalytic activity of the biological agent having catalytic activity.

10. The method of claim 1 , wherein the organic solution further comprises an organic solvent.

11. The method of claim 10 , wherein
the organic solution comprises as the liquid cation exchanger 20 to 80 vol % of oleic acid, and as the organic solvent lauric acid methyl ester,
the organic compound is 12-aminolauric acid methyl ester, and
a bacterial cell is present in the aqueous solution, wherein the bacterial cell comprises a recombinant alkane monooxygenase and a recombinant transaminase.

12. A reaction mixture comprising an aqueous solution and a hydrophobic organic solution, wherein the hydrophobic organic solution comprises a fatty acid as a liquid cation exchanger,
and wherein the aqueous solution comprises a compound of formula (I)
NH 3 + -A-COOR 1   (I),

wherein R 1 is hydrogen, methyl, ethyl or a negative charge and A is an unsubstituted, linear alkylene group comprising at least three carbon atoms, and
wherein the aqueous solution further comprises a cell comprising a recombinant alkane monooxygenase and a recombinant transaminase.

13. The method of claim 1 , wherein A in formula I is an unsubstituted, linear alkylene group comprising at least eight carbon atoms.

14. The method of claim 1 , wherein the contacting is performed at a temperature of 30 to 37° C.

15. The method of claim 1 , wherein the contacting is performed at a pH of 6.2 to 7.2.

16. The method of claim 1 , wherein the liquid cation exchanger is a fatty acid comprising 14 to 22 carbon atoms.

17. The method of claim 1 , wherein the liquid cation exchanger is a fatty acid comprising 16 to 18 carbon atoms.

18. The method of claim 1 , wherein the liquid cation exchanger is oleic acid or erucic acid.

Assignees

• Erhardt Frank
• Haas Thomas
• Roos Martin
• Demicoli Daniel
• Poetter Markus
• Schubert Anja
• Pfeffer Jan Christoph
• Tacke Thomas
• Haeger Harald
• Pfennig Andreas
• Przybylski-Freund Marie-Dominique
• Evonik Degussa Gmbh

Inventors

• Erhardt Frank
• Haas Thomas
• Roos Martin
• Demicoli Daniel
• Poetter Markus
• Schubert Anja
• Pfeffer Jan Christoph
• Tacke Thomas
• Haeger Harald
• Pfennig Andreas
• Przybylski-Freund Marie-Dominique

Classifications

• B01J39/16

  Organic material · CPC title

• C02F2001/425

  using cation exchangers · CPC title

• B01J39/04 Primary

  Processes using organic exchangers · CPC title

• C07C227/40

  Separation; Purification · CPC title

• C02F1/26

  by extraction · CPC title