Methods and apparatus for mixing and shipping fluids

Patent metadata

Field	Value
Publication number	US-9314751-B2
Application number	US-98670111-A
Country	US
Kind code	B2
Filing date	Jan 7, 2011
Priority date	Jan 7, 2011
Publication date	Apr 19, 2016
Grant date	Apr 19, 2016

Abstract

A method for mixing includes releasably coupling a first container station to a docking station, the first container station having a shipping vessel bounding a compartment, the docking station having a stand and a drive motor assembly adjustably mounted to the stand. The vertical or horizontal position of the drive motor assembly is adjusted relative to the stand so that the drive motor assembly is in a first position. A drive shaft is advanced through the drive motor assembly and into a chamber of a first collapsible bag disposed within the compartment of the shipping vessel. The drive motor assembly is activated so that the mixer rotates the drive shaft causing mixing of the fluid within the first collapsible bag.

First claim

What is claimed is:

1. A method for shipping a fluid, the method comprising:
removably securing a retention ring to a shipping vessel that bounds a chamber, the retention ring having a plurality of catches disposed thereon;
inserting a collapsible bag within the chamber of the shipping vessel so that a plurality of alignment tabs secured to the collapsible bag are removably secured to corresponding catches of the retention ring;
dispensing a fluid into a compartment of the collapsible bag, the shipping vessel being removably positioned on a movable first cart such that a lower end of the shipping vessel is supported on the first cart;
coupling the first cart directly to a first docking station, the first docking station comprising a stand and a first drive motor assembly mounted thereon;
mixing the fluid within the compartment of the collapsible bag by using the first drive motor assembly to rotate a drive shaft extending between the first drive motor assembly and the collapsible bag, the drive shaft passing into the chamber of the shipping vessel through an opening formed at an upper end of the shipping vessel, the upper end of the shipping vessel being disposed above the lower end of the shipping vessel;
separating the first cart from the first docking station;
removing the shipping vessel containing the collapsible bag and fluid from the first cart;
shipping the shipping vessel removed from the first cart and containing the collapsible bag and fluid to a second location;
positioning the shipping vessel on a movable second cart;
coupling the second cart to a second docking station, the second docking station comprising a stand and a second drive motor assembly mounted thereon; and
mixing the fluid within the compartment of the collapsible bag by using the second drive motor assembly to rotate a drive shaft extending between the second drive motor assembly and the collapsible bag.

2. The method as recited in claim 1 , wherein the shipping vessel comprises a plastic barrel.

3. The method as recited in claim 1 , where in the fluid comprises a media, buffer or reagent.

4. The method as recited in claim 1 , further comprising securing a lid to the shipping vessel prior to shipping the shipping vessel, the lid being completely removable from the shipping vessel.

5. The method as recited in claim 1 , wherein the step of mixing the fluid comprises:
advancing the drive shaft consecutively through a portion of the first drive motor assembly, through a hub rotatably mounted on the collapsible bag, and into an elongated tubular connector, the tubular connector having the hub mounted on a first end and an impeller mounted on an opposing second end; and
activating the first drive motor assembly so that the first drive motor assembly rotates the drive shaft which in turn rotates the impeller within the compartment of the collapsible bag.

6. The method as recited in claim 1 , further comprising removing the retention ring from the shipping vessel prior to shipping the shipping vessel to the second location.

7. A fluid mixing system comprising:
(i) a cart comprising:
a frame;
a plurality of wheels mounted to frame; and
a locking catch coupled to the frame;

(ii) a shipping vessel removably positioned on the frame of the cart such that a lower end of the shipping vessel is supported on the cart, the shipping vessel comprising:
an encircling sidewall bounding a chamber and extending between an upper end and an opposing lower end;
a support floor disposed within the chamber and dividing the chamber into an upper compartment and a lower compartment;
an opening extending through the support floor so as to provide communication between the upper compartment and the lower compartment; and
an access port extending through the sidewall at the lower end thereof so as to communicate with the lower compartment;

(iii) a container assembly comprising:
a collapsible bag bounding a compartment, the collapsible bag being at least partially disposed within the upper compartment of the chamber of the shipping vessel;

(iv) a docking station comprising:
a stand;
a locking assembly secured to the stand, the locking assembly engaging the locking catch of the cart so that the cart is releasably secured to the docking station; and
a drive motor assembly mounted to the stand; and

(v) an elongated drive shaft removably coupled with the drive motor assembly and removably coupled with a mixing element located within the compartment of the collapsible bag, the drive shaft passing into the chamber of the shipping vessel through an opening formed at an upper end of the shipping vessel, the upper end of the shipping vessel being disposed above the lower end of the shipping vessel, the drive motor assembly being configured to rotate the drive shaft.

8. The fluid mixing system as recited in claim 7 , wherein the container assembly further comprises:
a rotational assembly comprising a casing mounted to the collapsible bag and a hub rotatably mounted to the casing, the hub having a passageway extending therethrough;
the mixing element comprising an impeller; and
an elongated tubular connector extending between the hub and impeller, the drive shaft passing consecutively through the hub and into the tubular connector.

9. The fluid mixing system as recited in claim 7 , wherein the cart further comprises:
a plurality of legs upstanding from the frame; and
a support secured to the legs, the shipping vessel resting on the support.

10. The fluid mixing system as recited in claim 7 , wherein the shipping vessel comprises a plastic barrel.

11. The fluid mixing system as recited in claim 7 , further comprising a retention ring removably secured to the shipping vessel, the collapsible bag being removably secured to the retention ring.

12. The fluid mixing system as recited in claim 7 , further comprising a base floor disposed at the lower end of the sidewall so that the lower compartment is bounded between the support floor and the base floor.

13. The fluid mixing system as recited in claim 7 , further comprising a drain line extending from the collapsible bag, the drain line or collapsible bag passing through the opening on the support floor, the drain line passing through the access port.

14. The method for shipping a fluid as recited in claim 1 , wherein the drive shaft extending from the first drive motor engages an impeller disposed within the collapsible bag.

15. The method for shipping a fluid as recited in claim 1 , wherein the step of mixing the fluid within the compartment of the collapsible bag by using the first drive motor assembly includes the drive shaft passing into the chamber of the shipping vessel through an opening formed at an upper end of the shipping vessel.

16. The method for shipping a fluid as recited in claim 1 , wherein the step of mixing the fluid within the compartment of the collapsible bag by using the first drive motor assembly includes removably coupling the draft shaft to the first drive motor and removably coupling the draft shaft to a mixing element located within the compartment of the collapsible bag.

17. The method for shipping a fluid as recited in claim 1 , wherein the shipping vessel comprises:
an encircling sidewall bounding the chamber and extending between an upper end and an opposing lower end;
a support floor disposed within the chamber and dividing the chamber into an upper compartment and a lower compartment, the collapsible bag being at least partially disposed within the upper compartment;
an opening extending through the support floor s

Assignees

• Goodwin Michael E
• Lee Jacob D
• Woods Whitt F
• Draper Patrick L
• Life Technologies Corp

Inventors

• Goodwin Michael E
• Lee Jacob D
• Woods Whitt F
• Draper Patrick L

Classifications

• C12M29/06

  Nozzles; Sprayers; Spargers; Diffusers (per se B01F23/231, B01J19/26) · CPC title

• C12M23/26 Primary

  flexible (flexible containers for laboratory use B01L3/505) · CPC title

• B65B3/045

  for filling flexible containers having a filling and dispensing spout, e.g. containers of the "bag-in-box"-type · CPC title

• B65B1/02

  Machines characterised by the incorporation of means for making the containers or receptacles (from flat, folded, or tubular webs of flexible sheet material B65B9/00) · CPC title

• B01F2215/0431

  Numerical size values, e.g. diameter of a hole or conduit, area, volume, length, width, or ratios thereof · CPC title