Compositions and methods for forming stabilized compositions with reduced csa agglomeration
US-2015258121-A1 · Sep 17, 2015 · US
US9314472B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9314472-B2 |
| Application number | US-201314056122-A |
| Country | US |
| Kind code | B2 |
| Filing date | Oct 17, 2013 |
| Priority date | Oct 17, 2012 |
| Publication date | Apr 19, 2016 |
| Grant date | Apr 19, 2016 |
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Treating and Preventing mastitis employing cationic steroidal antimicrobials (CSAs). Treating or preventing clinical mastitis in a mammal includes administering a cationic steroidal anti-microbial compound (CSA) formulation to the intra-mammary organ of a mammal (e.g., a dairy cow), such as by injection into the mammary organ (e.g., through the teat of the mammary organ), and/or topical application. The dairy cow can be lactating and have a somatic cell count (SCC) less than or equal to 500,000 cells/mL at the time of administering the CSA formulation. Alternatively, the dairy cow can be lactating and have a somatic cell count (SCC) greater than 500,000 cells/mL at the time of administering the CSA formulation. The dairy cow can be taken out of production during the administration of the CSA formulation for a period of time of about 3 days or less, 2 days or less, or 1 day or less.
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What is claimed is: 1. A method for treating or preventing clinical mastitis in a mammal, comprising: administering an effective amount of a cationic steroidal anti-microbial compound (CSA) formulation that is effective in treating or preventing clinical mastitis caused by one or more different microbes, including at least clinical mastitis caused by Prototheca , to the intra-mammary organ of a mammal, the CSA formulation containing at least one CSA compound of Formula I, or a ph…
Human Necessities · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
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