Compositions and methods for treating mucositis
US-2024415798-A1 · Dec 19, 2024 · US
US9314465B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9314465-B2 |
| Application number | US-201414287014-A |
| Country | US |
| Kind code | B2 |
| Filing date | May 24, 2014 |
| Priority date | Jun 16, 2009 |
| Publication date | Apr 19, 2016 |
| Grant date | Apr 19, 2016 |
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The present specification discloses compositions comprising a plurality of therapeutic compound having antitussive activity and methods and uses for treating a coughing condition with such compositions.
Opening claim text (preview).
The invention claimed is: 1. A pharmaceutical composition comprising 0.5 mg/mL to 10 mg/mL of Theobromine and 0.25 mg/mL to 7.5 mg/mL of Dextromethorphan, wherein the pharmaceutical composition does not include an anti-histamine. 2. The pharmaceutical composition according to claim 1 , wherein the composition comprises 0.5 mg/mL to 6 mg/mL of Theobromine and 0.5 mg/mL to 5 mg/mL of Dextromethorphan. 3. The pharmaceutical composition according to claim 2 , wherein the composition comprises 1 mg/mL to 3 mg/mL of Theobromine and 1 mg/mL to 3 mg/mL of Dextromethorphan. 4. The pharmaceutical composition according to claim 3 , wherein the composition comprises 2 mg/mL of Theobromine and 1.5 mg/mL of Dextromethorphan. 5. A method of treating cough, the method comprising the step of administering a therapeutically-effective amount of the pharmaceutical composition of claim 1 . 6. The method according to claim 5 , wherein the composition comprises 0.5 mg/mL to 6 mg/mL of Theobromine and 0.5 mg/mL to 5 mg/mL of Dextromethorphan. 7. The method according to claim 6 , wherein the composition comprises 1 mg/mL to 3 mg/mL of Theobromine and 1 mg/mL to 3 mg/mL of Dextromethorphan. 8. The method according to claim 7 , wherein the composition comprises 2 mg/mL of Theobromine and 1.5 mg/mL of Dextromethorphan. 9. The method according to claim 5 , wherein the therapeutically-effective amount of the pharmaceutical composition comprises between 20 mg/day and 200 mg/day of Theobromine and 10 mg/day and 150 mg/day of Dextromethorphan. 10. The method according to claim 9 , wherein the therapeutically-effective amount of the pharmaceutical composition comprises between 40 mg/day and 160 mg/day of Theobromine and 30 mg/day and 120 mg/day of Dextromethorphan.
Morphinan derivatives, e.g. morphine, codeine · CPC title
Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca · CPC title
having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir · CPC title
Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00 · CPC title
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