System and method for determining target stimulation volumes

Patent metadata

Field	Value
Publication number	US-9310985-B2
Application number	US-201213431258-A
Country	US
Kind code	B2
Filing date	Mar 27, 2012
Priority date	May 15, 2008
Publication date	Apr 12, 2016
Grant date	Apr 12, 2016

Abstract

A system and method may include determining a target stimulation volume based on modifying a patient population image for which an efficacious volume had been determined. A system and method for suggesting stimulation devices may include determining which stimulation device is capable of producing an output volume of activation that most closely matches the target volume. A system and method for facilitating selection of stimulation parameters may include graphically identifying a maximum volume in which tissue is stimulatable by an implanted stimulation device. A system and method may pre-compute volumes of activation that result from a predetermined modification of programming settings. A system and method may transmit stimulation programming settings from a stimulation programming module to a stimulation generating device.

First claim

What is claimed is:

1. A computer-implemented method for determining a stimulation volume for a subject patient, the method comprising:
associating, by a computer processor, anatomical features in a first image, corresponding to an anatomical region of the subject patient, with corresponding anatomical features in a second image, corresponding to an anatomical region of at least one selected patient from a patient population, wherein a stimulation volume has been predetermined for the at least one selected patient; and
warping, by the processor, a combination of the second image and the stimulation volume predetermined for the at least one selected patient so that the anatomical features in the second image of the combination match the anatomical features in the first image, the warped combination thereby providing for the subject patient one of a target stimulation volume, defined by an outline of a region targeted to be activated by a stimulation, and a side effect stimulation volume, defined by an outline of a region, activation of which by a stimulation is estimated to cause a side effect.

2. The method of claim 1 , wherein the at least one selected patient is selected based on at least one clinical similarity with the subject patient.

3. The method of claim 2 , wherein the at least one similarity includes a similarity between at least a portion of the first image and at least a corresponding portion of the second image.

4. The method of claim 1 , wherein the second image is a composite image of anatomical regions of a plurality of selected patients from the patient population.

5. The method of claim 4 , wherein the anatomical region of the at least one selected patient is a composite anatomical region corresponding to the plurality of selected patients.

6. The method of claim 1 , further comprising:
repeating the steps of warping to thereby provide the target stimulation volume responsive to a detected modification of the predetermined stimulation volume.

7. The method of claim 6 , wherein the predetermined stimulation volume is modified in response to a recorded behavioral response of the at least one selected patient resulting from a stimulation treatment.

8. A computer-implemented method for determining a stimulation volume for a subject patient, the method comprising:
associating, by a computer processor, anatomical features in a first image, corresponding to an anatomical region of the subject patient, with corresponding anatomical features in a second image, corresponding to an anatomical region of at least one selected patient from a patient population, wherein a stimulation volume has been predetermined for the at least one selected patient;
modifying, by the processor, the second image so that spatial relationships of the anatomical features in the second image match spatial relationships of the anatomical features in the first image;
modifying a spatial relationship of the stimulation volume to the second image based on the modification to the second image to generate a new spatial relationship; and
determining for the subject patient one of a target stimulation volume, defined by an outline of a region targeted to be activated by a stimulation, and a side effect stimulation volume, defined by an outline of a region, activation of which by a stimulation is estimated to cause a side effect, by applying the new spatial relationship to the modified second image.

Assignees

• Blum David Arthur
• Kokones Scott
• Moffitt Michael A
• Barnhorst Jordan
• Carlton Keith
• Boston Scient Neuromodulation

Inventors

• Blum David Arthur
• Kokones Scott
• Moffitt Michael A
• Barnhorst Jordan
• Carlton Keith

Classifications

• G06T12/00

  Tomographic reconstruction from projections · CPC title

• A61B34/25

  User interfaces for surgical systems · CPC title

• G06T7/30

  Determination of transform parameters for the alignment of images, i.e. image registration · CPC title

• A61N1/37247

  User interfaces, e.g. input or presentation means · CPC title

• G06T2207/10072

  Tomographic images · CPC title