Recombinant respiratory syncytial virus strains comprising NS1 and NS2 gene shifts
US-11918638-B2 · Mar 5, 2024 · US
Recombinant virus-like particles encoded by multi-gene vector
US9309536B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9309536-B2 |
| Application number | US-201414472911-A |
| Country | US |
| Kind code | B2 |
| Filing date | Aug 29, 2014 |
| Priority date | May 1, 2009 |
| Publication date | Apr 12, 2016 |
| Grant date | Apr 12, 2016 |
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Abstract
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The invention describes novel virus-like particles for use as vaccines, diagnostic tools and R&D tools based on recombinant DNA and cell cultivation techniques for production. The recombinant virus-like particles of the invention are assembled by polypeptide chains that incorporate several, in particular two or more, different epitopes which are selected either (a) from different viral strains of the same virus and/or (b) from different serotypes of the same virus and/or (c) from different viral strains specific for different hosts. These epitopes are then displayed on the particle surface.
First claim
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The invention claimed is: 1. A single baculoviral vector encoding a recombinant virus-like particle comprising two or more different surface proteins comprising epitopes, wherein the surface proteins are selected from (a) different viral strains of a same virus type, (b) different serotypes of a same virus type, or (c) different viral strains of a same virus type specific for different hosts; and wherein the baculoviral vector comprises a polynucleotide sequence selected from SEQ I…
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- What does patent US9309536B2 cover?
- The invention describes novel virus-like particles for use as vaccines, diagnostic tools and R&D tools based on recombinant DNA and cell cultivation techniques for production. The recombinant virus-like particles of the invention are assembled by polypeptide chains that incorporate several, in particular two or more, different epitopes which are selected either (a) from different viral strains …
- Who is the assignee on this patent?
- Pfizer
- What technology area does this patent fall under?
- Primary CPC classification C12N7/04. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Apr 12 2016 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).