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Polyethylene glycol based oligomers for coating nanoparticles, nanoparticles coated therewith, and related methods
US9309432B1 · US · B1
| Field | Value |
|---|---|
| Publication number | US-9309432-B1 |
| Application number | US-201313772632-A |
| Country | US |
| Kind code | B1 |
| Filing date | Feb 21, 2013 |
| Priority date | Sep 9, 2011 |
| Publication date | Apr 12, 2016 |
| Grant date | Apr 12, 2016 |
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- Title
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Abstract
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In a composition aspect of the invention, a nanoparticle coating comprises repeating polyacrylic acid monomers covalently bound together in an aliphatic chain having a plurality of carboxylic acid functional groups and modified carboxylic acid functional groups extending therefrom. A first portion of the modified carboxylic acid functional groups are modified by a PEG oligomer having a terminal methoxy functional group and a second portion of the modified carboxylic acid functional groups are modified by a PEG oligomer having at least one terminal catechol group.
First claim
Opening claim text (preview).
That which is claimed is: 1. A composition comprising repeating polyacrylic acid monomer units covalently bound together in an aliphatic chain having a plurality of carboxylic acid functional groups and modified carboxylic acid functional groups extending therefrom, wherein a first portion of the modified carboxylic acid functional groups are modified by a PEG oligomer having a terminal methoxy functional group and a second portion of the modified carboxylic acid functional groups are modified by a PEG oligomer having at least one terminal catechol group. 2. The composition of claim 1 , wherein the PEG oligomer having a terminal methoxy functional group comprises a PEG chain having a terminal amine group opposite the terminal methoxy functional group, the terminal amine group being covalently bound to a carbonyl carbon of a modified carboxylic acid functional group. 3. The composition of claim 1 , wherein the PEG oligomer having at least one terminal catechol group is dopamine. 4. The composition of claim 1 , further comprising a third portion of modified carboxylic acid functional groups wherein the third portion of the modified carboxylic acid functional groups are modified by a PEG oligomer having functional group. 5. The composition of claim 1 , wherein the number of polyacrylic acid monomer units is between about 20 to about 30.
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Classifications
Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers · CPC title
Homopolymers and copolymers of compounds having one or more unsaturated aliphatic radicals each having only one carbon-to-carbon double bond, and at least one being terminated by a carboxyl radical and containing at least one other carboxyl radical in the molecule; Salts, anhydrides, esters, amides, imides or nitriles thereof · CPC title
Esters containing oxygen in addition to the carboxy oxygen · CPC title
Acrylic acid; Methacrylic acid; Metal salts or ammonium salts thereof · CPC title
- C09D133/02Primary
Homopolymers or copolymers of acids; Metal or ammonium salts thereof · CPC title
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- What does patent US9309432B1 cover?
- In a composition aspect of the invention, a nanoparticle coating comprises repeating polyacrylic acid monomers covalently bound together in an aliphatic chain having a plurality of carboxylic acid functional groups and modified carboxylic acid functional groups extending therefrom. A first portion of the modified carboxylic acid functional groups are modified by a PEG oligomer having a terminal…
- Who is the assignee on this patent?
- Univ Florida State Res Found
- What technology area does this patent fall under?
- Primary CPC classification C09D133/02. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Apr 12 2016 00:00:00 GMT+0000 (Coordinated Universal Time) (B1). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).