C-3 substituted bicyclooctane based HIV protease inhibitors

US9309213B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-9309213-B2
Application numberUS-201214131849-A
CountryUS
Kind codeB2
Filing dateJul 11, 2012
Priority dateJul 11, 2011
Publication dateApr 12, 2016
Grant dateApr 12, 2016

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Abstract

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C3-functionalized-cyclopentanyltetrahydrofuranyl carbamates that inhibit HIV proteolytic enzymes and processes for preparing the compounds are described. Compositions comprising the disclosed compound and methods of using the compounds and/or compositions for treating patients infected with HIV are also described.

First claim

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What is claimed is: 1. A compound having the formula or a pharmaceutically acceptable salt, isomer, mixture of isomers, crystalline form, non crystalline form, hydrate, or solvate thereof; wherein X 1 is C(O), S(O), S(O) 2 , HNS(O) 2 , HNC(O), or C(O)NH; R 1 and R 2 are in each instance independently selected from the group consisting of hydrogen, and a prodrug form…

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What does patent US9309213B2 cover?
C3-functionalized-cyclopentanyltetrahydrofuranyl carbamates that inhibit HIV proteolytic enzymes and processes for preparing the compounds are described. Compositions comprising the disclosed compound and methods of using the compounds and/or compositions for treating patients infected with HIV are also described.
Who is the assignee on this patent?
Ghosh Arun K, Mitsuya Hiroaki, Chapsal Bruno D, and 1 more
What technology area does this patent fall under?
Primary CPC classification C07D307/935. Mapped technology areas include Chemistry & Metallurgy.
When was this patent published?
Publication date Tue Apr 12 2016 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).