Organic electroluminescent materials and devices
US-2015372243-A1 · Dec 24, 2015 · US
US9309212B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9309212-B2 |
| Application number | US-201214119541-A |
| Country | US |
| Kind code | B2 |
| Filing date | May 22, 2012 |
| Priority date | May 24, 2011 |
| Publication date | Apr 12, 2016 |
| Grant date | Apr 12, 2016 |
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The present invention embraces compounds that modulate the activity of Epstein-Barr Nuclear Antigen 1 (BBNA1) protein and use thereof in methods for treating latent Epstein-Barr virus infection. R7 is a substituted or unsubstituted phenyl, pyridyl, or pyrimidinyl group. A pharmaceutical composition comprising a compound of the invention in admixture with a pharmaceutically acceptable carrier is also provide as are methods for modulating the activity of Epstein-Barr Nuclear Antigen 1 (EBNA1) protein and treating a latent EpsteinBarr virus infection with a composition of the present invention.
Opening claim text (preview).
What is claimed is: 1. A method for inhibiting the activity of Epstein-Barr Nuclear Antigen 1 (EBNA1) protein comprising contacting an EBNA1 protein with an effective amount of a compound of Formula III: wherein R 7 is a substituted or unsubstituted phenyl, pyridyl, or pyrimidinyl group, so that the activity of the EBNA1 protein is inhibited. 2. A met…
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
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