Synthetic peptide, and cosmetic composition or pharmaceutical composition and application thereof
US-2024352069-A1 · Oct 24, 2024 · US
US9303064B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9303064-B2 |
| Application number | US-201114343850-A |
| Country | US |
| Kind code | B2 |
| Filing date | Nov 2, 2011 |
| Priority date | Sep 9, 2011 |
| Publication date | Apr 5, 2016 |
| Grant date | Apr 5, 2016 |
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A peptide inhibiting a matrix metalloproteinase activity, thereby improving the condition of skin and a composition containing the peptide is described, where the peptide comprises an amino acid sequence represented by the formula: X aa1 -X aa2 -Pro-Cys-X aa3 -X aa4 -X aa5 -Ser-X aa6 and has excellent bioactivities of inhibiting the activity of hyaluronic acid degrading enzymes, adipogenesis in fat cells, angiogenesis, and the like, thereby being useful for the treatment of various disease such as obesity, cancer, and inflammation.
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What is claimed is: 1. A peptide inhibiting a matrix metalloproteinase activity, consisting of an amino acid sequence selected from the group consisting of SEQ ID NOs: 1-3. 2. The peptide according to claim 1 , wherein the peptide have facilitation ability of cell growth. 3. The peptide according to claim 1 , wherein the peptide inhibits cell death by oxidative stress. 4. The peptide according to claim 1 , wherein the p…
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