Substituted 3-haloallylamine inhibitors of SSAO and uses thereof
US-10160723-B2 · Dec 25, 2018 · US
US9302986B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9302986-B2 |
| Application number | US-201314397931-A |
| Country | US |
| Kind code | B2 |
| Filing date | Apr 5, 2013 |
| Priority date | May 2, 2012 |
| Publication date | Apr 5, 2016 |
| Grant date | Apr 5, 2016 |
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The preparation and pharmaceutical use of substituted 3-haloallylamine derivatives as SSAO/VAP-1 inhibitors having the structure of Formula I: is described. Methods of using compounds of Formula I, or pharmaceutically acceptable salt or derivatives thereof, for the treatment of a variety of indications, e.g., inflammatory diseases, ocular diseases, fibrotic diseases, diabetes-induced diseases and cancer, are also described.
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The invention claimed is: 1. A compound selected from the group consisting of: 1 2…
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