Continuous reaction micro-reactor

Patent metadata

Field	Value
Publication number	US-9302243-B2
Application number	US-74361310-A
Country	US
Kind code	B2
Filing date	May 12, 2010
Priority date	May 12, 2009
Publication date	Apr 5, 2016
Grant date	Apr 5, 2016

Abstract

A continuous reaction micro-reactor of modular structure comprises, arranged along a back-to-front stacking axis thereof, a first frame means, a reaction unit, and a second frame means, wherein said reaction unit comprises a process fluid channel system for continuous reaction of a plurality of feeds or reactants flowing into said reaction unit to form at least one product flowing out of said reaction unit, and a heat exchange fluid channel system for adjusting the temperature environment of said process fluid channel system, said first and second frame means are each formed as a flange, and said first and second frame means are alpressed towards each other by a plurality of tensioning means arranged along and within an outer circumference of said first and second frame means and enclosing said reaction unit.

First claim

The invention claimed is:

1. A continuous reaction micro-reactor of modular structure comprising, arranged along a back-to-front stacking axis thereof, a first frame means, a reaction unit, and a second frame means, wherein:
said reaction unit comprises a process fluid channel system for continuous reaction of a plurality of feeds or reactants flowing into said reaction unit to form at least one product flowing out of said reaction unit, a heat exchange fluid channel system for adjusting the temperature environment of said process fluid channel system and a transparent cover plate;
said first and second frame means are each formed as a flange;
said first and second frame means are pressed towards each other by a plurality of tensioning means arranged along and within an outer circumference of said first and second frame means;
said second frame means is configured to allow the process fluid channel system to be inspected via the cover-plate being transparent;
said reaction unit can separately be exchanged to adapt it to multifarious technological problems to be investigated and solved; and
said process fluid channel system comprises a micro-structure formed into a reaction surface of said reaction unit, said micro-structure comprising open grooves having a bottom defining a depth, the grooves forming the fluid channel system, wherein said open grooves are fluid-tightly covered by said cover plate, leaving inlet and outlet openings for the various feeds and products at side surfaces of the reaction unit.

2. The continuous reaction micro-reactor of claim 1 , wherein:
said reaction unit comprises a plate-shaped process sub-module, a front surface of which having said process fluid channel system, and a plate-shaped heat exchange sub-module sandwiched between said process sub-module and said first frame means, and
said heat exchange fluid channel system comprises a micro-structure formed into a front surface of said heat exchange sub-module and covered by a back surface of said process sub-module in a manner to seal said heat exchange fluid channel system.

3. The continuous reaction micro-reactor of claim 2 , wherein said heat exchange sub-module and said first frame means are made of one part.

4. The continuous reaction micro-reactor of claim 1 , wherein:
said reaction unit comprises a plate-shaped process and heat exchange sub-module, a front surface of which having said process fluid channel system, and a second cover-plate sandwiched between said process and heat exchange sub-module and said first frame means, and
said heat exchange fluid channel system comprises a micro-structure formed into a back surface of said heat exchange sub-module and covered by said second cover-plate in a manner to seal said heat exchange fluid channel system.

5. The continuous reaction micro-reactor of claim 4 , wherein said process and heat exchange sub-module is divided by a plane perpendicular to said stacking axis into a first plate-shaped sub-module body including said process fluid channel system and a second plate-shaped sub-module body including said heat exchange channel system.

6. The continuous reaction micro-reactor of claim 4 , wherein said second cover-plate and said first frame means are made of one part.

7. The continuous reaction micro-reactor of claim 1 , wherein said second frame means is configured such as to allow an external fluid connection of said cover-plate through the second frame means to serve as a fluid inlet means for said process fluid channel system.

8. The continuous reaction micro-reactor according to claim 1 , wherein the surface of said cover-plate directly covering said process fluid channel system carries a catalytic coating.

9. The continuous reaction micro-reactor according to claim 1 , wherein said reaction unit has a plurality of primary inlet ports for a plurality of primary feeds flowing into said process fluid channel system, and at least one secondary inlet port provided after said plurality of primary inlet ports in a flow direction for at least one secondary feed flowing into said process fluid channel system.

10. The continuous reaction micro-reactor according to claim 9 , wherein said primary and/or secondary inlet ports are arranged on side surfaces and/or on front and back surfaces of the reaction unit.

11. The continuous reaction micro-reactor according to claim 1 , wherein said process fluid channel system and/or said heat exchange fluid channel system are/is formed in a meandered fashion.

12. The continuous reaction micro-reactor according to claim 1 , wherein said process fluid channel system comprises, consecutively arranged in a flow direction of said primary feeds flowing through it, at least one turbulent-flow mixing zone and at least one essentially laminar-flow retention zone.

13. The continuous reaction micro-reactor according to claim 1 , wherein said first and second frame means have first and second positioning means, respectively, that define a position of said reaction unit relative to the stacking axis.

14. The continuous reaction micro-reactor according to claim 13 , wherein said first and second positioning means are formed as recesses in surfaces of said first and second frame means, respectively, facing each other, wherein the inner circumferential shape of the recesses is commensurate to the outer circumferential shape of corresponding side of said reaction unit.

15. The continuous reaction micro-reactor according to claim 14 , wherein said recesses forming said first and second positioning means are rectangular.

16. A continuous reaction micro-reactor of modular structure comprising:
a flange-shaped first frame means;
a heat exchange module comprising a plate having a major surface and a side surface, said plate having a heat exchange fluid channel system for adjusting the temperature environment of the micro-reactor, said heat exchange fluid channel system comprising an open groove formed in said major surface, said groove having a bottom defining a depth less than the thickness of said heat exchange module plate, said heat exchange fluid channel system further comprising at least one inlet disposed in said side surface of said plate for a heat exchange fluid flowing into said heat exchange module and at least one outlet for the heat exchange fluid flowing out of heat exchange module;
a process module arranged on the heat exchange module along a back-to-front stacking axis, said process module comprising a plate having a front-facing reaction surface and a micro-structure formed into said reaction surface, said micro structure comprising at least one open meandering groove, said meandering groove having a bottom defining a depth less than the thickness of said process module plate and forming a process fluid channel system for continuous reaction of a plurality of feeds or reactants flowing into said process module to form at least one product flowing out of said process module, said process module further including at least one inlet disposed on a side surface thereof for the plurality of feeds or reactants flowing into said process module and at least one outlet for the at least one product flowing out of said process module;
a transparent cover plate arranged on the process module along the back-to-front stacking axis, said transparent cover plate directly covering said at least one open meandering groove formed in said front-facing reaction surface of said process module plate in a manner to seal and close said process fluid channel system;
a flange-shaped second frame means arranged on the transparent cover plate along a back-to-front s

Assignees

• Kockmann Norbert Josef
• Lonza Ag

Inventors

• Kockmann Norbert Josef

Classifications

• B01J2219/00889

  Mixing · CPC title

• B01J2219/00835

  Comprising catalytically active material · CPC title

• B01J2219/00891

  Feeding or evacuation · CPC title

• B01J2219/0081

  Plurality of modules · CPC title

• B01J19/0093 Primary

  Microreactors, e.g. miniaturised or microfabricated reactors (laboratory containers with capillary fluid transport in microfabricated channels or chambers B01L3/5027) · CPC title