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Sample component trapping, release, and separation with membrane assemblies interfaced to electrospray mass spectrometry

US9302225B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-9302225-B2
Application numberUS-201313942548-A
CountryUS
Kind codeB2
Filing dateJul 15, 2013
Priority dateMay 19, 2005
Publication dateApr 5, 2016
Grant dateApr 5, 2016

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  1. Title

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  2. Abstract

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  3. Assignees and inventors

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  4. Key dates

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  5. First independent claim

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  6. CPC / IPC classifications

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  7. Citations and related patents

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Abstract

Official abstract text for this publication.

A method and apparatus to trap, release and/or separate sample components in solution passing through a channel with or without packing material present by passing ion current through the channel driven by an electric field. A portion of the ion current includes cation and/or anion species generated from second solution flows separated from the sample solution flow path by semipermeable membranes. Cation and/or anion species generated in the second solution flow regions are transferred into the sample solution flow path through ion selective semipermeable membranes. Ion current moving along the sample solution flow path is controlled by varying the composition of the second solutions and/or changing the voltage between membrane sections for a given sample solution composition. The sample composition may also be varied separately or in parallel to enhance trapping, release and/or separation efficiency and range.

First claim

Opening claim text (preview).

We claim: 1. An apparatus for analyzing chemical species, comprising: a. at least one membrane assembly each configured with a semipermeable membrane separating a first flow channel and a second flow channel, and an electrode positioned in the second flow channel; b. a fluid delivery system configured to introduce a sample into the first flow channel; c. an ion source interfaced to an outlet of the first flow channel of the at least one membrane assembly so that the sample is…

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Frequently asked questions

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What does patent US9302225B2 cover?
A method and apparatus to trap, release and/or separate sample components in solution passing through a channel with or without packing material present by passing ion current through the channel driven by an electric field. A portion of the ion current includes cation and/or anion species generated from second solution flows separated from the sample solution flow path by semipermeable membran…
Who is the assignee on this patent?
Perkinelmer Health Sci Inc
What technology area does this patent fall under?
Primary CPC classification B01D59/44. Mapped technology areas include Operations & Transport.
When was this patent published?
Publication date Tue Apr 05 2016 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).