Compositions and methods for treating mucositis
US-2024415798-A1 · Dec 19, 2024 · US
US9301972B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9301972-B2 |
| Application number | US-201414537464-A |
| Country | US |
| Kind code | B2 |
| Filing date | Nov 10, 2014 |
| Priority date | Dec 6, 2006 |
| Publication date | Apr 5, 2016 |
| Grant date | Apr 5, 2016 |
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The present invention relates to an injection solution for intra-articular administration for treating arthritic disorders comprising a cross-linked hyaluronic acid derivative wherein part of functional groups of a hyaluronic acid are cross-linked with a cross-linking group to the extent of 0.6 to 15% of cross-linking extent as an active ingredient in an amount having a long-lasting analgesic effect and a pharmaceutically acceptable carrier, and an analgesic composition for suppressing a cartilage degeneration caused by arthritic disorders or a composition for suppressing a cartilage degeneration or an inflammation of synovium caused by arthritic disorders each comprising the cross-linked hyaluronic acid derivative and a pharmaceutically acceptable carrier.
Opening claim text (preview).
The invention claimed is: 1. A solution of a hyaluronic acid derivative in a pharmaceutically acceptable aqueous medium in an amount of 0.1% to 2% by weight based upon the total weight of the solution, the hyaluronic acid derivative comprising cross-linkable groups introduced into some functional groups of hyaluronic acid, the hyaluronic acid derivative having following characteristics: (1) the cross-linkable groups are a residue of cinnamic acid or a cinnamic acid derivative, and…
Human Necessities · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
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