Cyclohexyl beta-hydroxy alkyl amines and medical uses thereof
US-2024390298-A1 · Nov 28, 2024 · US
US9301939B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9301939-B2 |
| Application number | US-201514702022-A |
| Country | US |
| Kind code | B2 |
| Filing date | May 1, 2015 |
| Priority date | Jun 21, 2011 |
| Publication date | Apr 5, 2016 |
| Grant date | Apr 5, 2016 |
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Provided is a method for producing a chlorogenic acids composition having a reduced caffeine content and good taste and favor, capable of efficiently recovering high purity of chlorogenic acids from a chlorogenic acids-containing composition. The method for producing a purified chlorogenic acids composition comprises a step A of bringing a chlorogenic acids-containing composition into contact with a cation exchange resin; a step B of bringing the liquid obtained in the step A into contact with an anion exchange resin; and a step C of bringing an eluent into contact with the anion exchange resin after the step B.
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The invention claimed is: 1. A purified chlorogenic acids composition derived from a coffee bean extract, wherein a ratio (mass ratio) of protein/chlorogenic acids is 0.1 or smaller, a ratio (mass ratio) of citric acid/chlorogenic acids is 0.05 or larger, a ratio (mass ratio) of sucrose/chlorogenic acids is 0.4 or smaller, and a content of chlorogenic acids in solids is 60 mass % or larger. 2. The purified chlorogenic acids composition according to claim 1 , wherein a ratio (mass ratio) of sucrose/chlorogenic acids is 0.1 or smaller. 3. The purified chlorogenic acids composition according to claim 1 , wherein a ratio (mass ratio) of malic acid/chlorogenic acids is 0.02 or larger. 4. The purified chlorogenic acids composition according to claim 1 , wherein the ratio of protein/chlorogenic acids is 0.01 or larger. 5. The purified chlorogenic acids composition according to claim 1 , wherein the ratio of citric acid/chlorogenic acids is 0.5 or smaller. 6. The purified chlorogenic acids composition according to claim 1 , wherein the content of chlorogenic acids in solids is from 60 to 90 mass %. 7. The purified chlorogenic acids composition according to claim 1 , wherein a ratio (mass ratio) of malic acid/chlorogenic acids is 0.3 or smaller.
Coffea, e.g. coffee · CPC title
of acids having aromatic rings, e.g. benactizyne, clofibrate · CPC title
in the strongly basic form · CPC title
in the weakly acidic form · CPC title
in the strongly acidic form · CPC title
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