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Method and system for in-vivo temperature measurement based on AC magnetization of magnetic nanoparticle
US9301693B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9301693-B2 |
| Application number | US-201314232600-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jun 25, 2013 |
| Priority date | Mar 1, 2013 |
| Publication date | Apr 5, 2016 |
| Grant date | Apr 5, 2016 |
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Abstract
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The invention discloses a method for in-vivo temperature measurement based on AC magnetization of magnetic nanoparticles, and relates to a nano test technology field. The invention positions magnetic nano agent at an area of a measured object, applies an AC excitation magnetic field to the area of the magnetic nano agent, collects an AC magnetization signal of the magnetic nano agent under the AC excitation magnetic field, detects amplitudes of odd harmonics of the AC magnetization signal, and finally calculates in-vivo temperature according to a relationship between the odd harmonics and the in-vivo temperature. The invention predetermines the relationship between the odd harmonics and the in-vivo temperature via the discrete Langevin's function and the Fourier transformation, solves the in-vivo temperature according to the relationship without considering concentration of the magnetic nanoparticles, and effective moment as temperature varies, and thus accurately detecting the in-vivo temperature.
First claim
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What is claimed is: 1. A method for in-vivo temperature measurement, comprising steps of: (1) positioning a magnetic nano agent at an area of a measured object; (2) applying an AC excitation magnetic field to said area; (3) collecting an AC magnetization signal of said magnetic nano agent under said AC excitation magnetic field using a coil sensor and processing the AC magnetization signal via a data acquisition card; (4) detecting amplitudes C 1 , C 3 , . . . , C 2n-1 of o…
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Physics · mapped topic
- A61B5/01Primary
Human Necessities · mapped topic
Physics · mapped topic
Physics · mapped topic
Human Necessities · mapped topic
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- What does patent US9301693B2 cover?
- The invention discloses a method for in-vivo temperature measurement based on AC magnetization of magnetic nanoparticles, and relates to a nano test technology field. The invention positions magnetic nano agent at an area of a measured object, applies an AC excitation magnetic field to the area of the magnetic nano agent, collects an AC magnetization signal of the magnetic nano agent under the …
- Who is the assignee on this patent?
- Univ Huazhong Science Tech
- What technology area does this patent fall under?
- Primary CPC classification A61B5/01. Mapped technology areas include Human Necessities.
- When was this patent published?
- Publication date Tue Apr 05 2016 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).