Dosimeter, therapeutic apparatus, and computer program product for measuring radiation dosage to a subject during magnetic resonance imaging

Patent metadata

Field	Value
Publication number	US-9297906-B2
Application number	US-201113820851-A
Country	US
Kind code	B2
Filing date	Sep 7, 2011
Priority date	Sep 9, 2010
Publication date	Mar 29, 2016
Grant date	Mar 29, 2016

Abstract

A dosimeter measures radiation dosage to a subject during a magnetic resonance imaging guided radiation therapy session. The dosimeter includes an outer surface configured to receive a surface of the subject, and discrete cells. Each of the discrete cells is filled with a magnetic resonance radiation dosimeter.

First claim

The invention claimed is:

1. A dosimeter for measuring radiation dosage to a subject during a magnetic resonance imaging guided radiation therapy session, the dosimeter comprising:
a housing having a housing surface adapted for receiving a surface of the subject;
discrete cells each filled with a magnetic resonance radiation dosimeter material; and
foam balls, wherein the discrete cells and the foam balls are mixed in the housing.

2. The dosimeter of claim 1 , wherein the dosimeter further comprises a thermal insulation layer between the housing surface and the discrete cells.

3. The dosimeter of claim 1 , wherein the dosimeter is a pillow.

4. The dosimeter of claim 1 , wherein the dosimeter comprises at least two cushions configured for mounting to a patient support of a magnetic resonance imaging system, and wherein the at least two cushions are configured to support the subject.

5. The dosimeter of claim 1 , wherein the dosimeter comprises two parts, wherein each of the two parts has a respective surface adapted for receiving two opposing surfaces of the subject.

6. The dosimeter of claim 1 , wherein the magnetic resonance radiation dosimeter material is one of a Fricke gel and a polymer gel.

7. A therapeutic apparatus comprising:
a magnetic resonance imaging system adapted for acquiring a set of magnetic resonance data from an imaging zone;
an ionizing radiation source adapted for directing a beam of ionizing radiation towards a target zone within a subject; a computer system with a processor;
a non-volatile computer-readable storage medium containing machine-executable instructions for execution by the processor; and
a dosimeter having a housing, the housing having a housing surface adapted for receiving a surface of the subject,
discrete cells each filled with a magnetic resonance radiation dosimeter material, and foam balls, wherein the discrete cells and the foam balls are mixed in the housing,
wherein execution of the instructions causes the processor to perform acts of:
determining a position of the target zone,
directing the beam of ionizing radiation into the target zone using the position of the target zone, wherein the ionizing radiation is directed such that the ionizing radiation passes through the dosimeter,
acquiring a set of magnetic resonance data from the dosimeter using the magnetic resonance imaging system, wherein the dosimeter is at least partially within the imaging zone,
calculating a dosage of ionizing radiation to the subject in accordance with the set of magnetic resonance data acquired from the dosimeter.

8. The therapeutic apparatus of claim 7 , wherein the acts of acquiring and calculating are performed simultaneously with the directing, wherein execution of the instructions further cause the processor to adjust at least one of a shape of the target zone, the position of the target zone and intensity of the radiation beam in accordance with the dosage.

9. The therapeutic apparatus of claim 8 , wherein a dosage of ionizing radiation in the target zone is calculated in accordance with the set of magnetic resonance data from the dosimeter.

10. The therapeutic apparatus of claim 7 , wherein the determining act is accomplished by any one of the following acts: using a registered coordinate system determined preoperatively, and determining the position of the target zone in accordance with the magnetic resonance data.

11. The therapeutic apparatus of claim 7 , wherein the instructions further cause the processor to perform an act of calculating a dosage distribution map in the subject in accordance with the magnetic resonance data.

12. The therapeutic apparatus of claim 7 , wherein the instructions further cause the processor to perform an act of directing the ionizing radiation through a second dosimeter, wherein the second dosimeter is at least partially within the imaging zone, wherein the instructions further cause the processor to perform an act of calculating a dose absorption map in the subject in accordance with the magnetic resonance data.

13. A non-transitory computer readable medium comprising machine executable instructions for execution by a processor of a computer system for controlling a therapeutic apparatus; wherein the therapeutic apparatus comprises a magnetic resonance imaging system adapted for acquiring a set of magnetic resonance data in an imaging zone; wherein the therapeutic apparatus further comprises an ionizing radiation source adapted for directing a beam of ionizing radiation towards a target zone within a subject; wherein the imaging zone comprises the target zone; and wherein execution of the instructions causes the processor to perform the acts of:
determining a position of the target zone;
directing the beam of ionizing radiation towards the target zone using the position of the target zone;
acquiring a set of magnetic resonance data from a dosimeter using the magnetic resonance imaging system, wherein the dosimeter comprises a housing having a housing surface adapted for receiving a surface of the subject, discrete cells each filled with a magnetic resonance radiation dosimeter material and foam balls, wherein the discrete cells and the foam balls are mixed in the housing;
calculating a dosage of ionizing radiation to the subject in accordance with the set of magnetic resonance data; and
adjusting at least one of a shape of the target zone, the position of the target zone and intensity of the radiation beam in accordance with the dosage.

Assignees

• Uhlemann Falk
• Koninkl Philips Nv

Inventors

• Uhlemann Falk

Classifications

• A61B5/0036

  including treatment, e.g., using an implantable medical device, ablating, ventilating · CPC title

• A61N5/1049

  for verifying the position of the patient with respect to the radiation beam · CPC title

• G01T1/04

  Chemical dosimeters (G01T1/06, G01T1/08 take precedence) · CPC title

• A61N2005/1055

  using magnetic resonance imaging [MRI] · CPC title

• G01R33/4808

  Multimodal MR, e.g. MR combined with positron emission tomography [PET], MR combined with ultrasound or MR combined with computed tomography [CT] · CPC title