Modification of surfaces with nanoparticles

Patent metadata

Field	Value
Publication number	US-9296870-B2
Application number	US-84463510-A
Country	US
Kind code	B2
Filing date	Jul 27, 2010
Priority date	Jul 27, 2009
Publication date	Mar 29, 2016
Grant date	Mar 29, 2016

Abstract

Methods for functionalizing a surface of a substrate with nanoparticles are described. In certain embodiments, the method can include attaching a plurality of photoactive linker to nanoparticles to obtain photoactive nanoparticles, wherein each photoactive linker comprises a binding group that attaches to the nanoparticles and a photoactive group; depositing the photoactive nanoparticles to the surface of the substrate, wherein the surface of the substrate comprises reactive groups that are capable of reacting with the photoactive groups; and irradiating the photoactive nanoparticles with radiation to react the photoactive group with the reactive group and to functionalize the surface of the substrate with nanoparticles. In certain embodiments, the method can include attaching a plurality of photoactive linker linkers to a surface of a substrate to obtain a photoactive surface, wherein each photoactive linker comprises a photoactive group and a binding group that attaches to the surface of the substrate; depositing nanoparticles to the photoactive surface, wherein the nanoparticles comprise reactive groups that are capable of reacting with the photoactive groups; and irradiating the photoactive surface with radiation to react the photoactive group with the reactive group to functionalize the surface of the substrate with nanoparticles.

First claim

The invention claimed is:

1. A method for functionalizing a surface of a substrate with nanoparticles, the method comprising:
attaching a plurality of photoactive linker to nanoparticles to obtain photoactive nanoparticles, wherein each photoactive linker comprises a binding group that attaches to the nanoparticles and a photoactive group, wherein the photoactive group is selected from the group consisting of a phthalimide, benzophenone, xanthone, thioxanthone, phenyl diazirine and combinations thereof;
depositing the photoactive nanoparticles to the surface of the substrate, wherein the surface of the substrate comprises hydrogen-containing reactive groups; and
irradiating the photoactive nanoparticles with radiation to react the photoactive group with the hydrogen-containing reactive group and to functionalize the surface of the substrate with nanoparticles.

2. The method of claim 1 , further comprising:
applying a mask having a pre-selected pattern to the surface of the substrate prior to said irradiating.

3. The method of claim 1 , wherein the nanoparticles are selected from the group consisting of metal oxide nanoparticles, gold nanoparticles, quantum dots, magnetic nanoparticles, photonic nanoparticles, and drug delivery nanoparticles.

4. The method of claim 1 , wherein the nanoparticles have at least one dimension of about 10 to about 100 nm.

5. The method of claim 1 , wherein the photoactive linker further comprises a spacer.

6. The method of claim 1 , wherein the substrate comprises an organic material comprising C—H bonds, N—H bonds, or S—H bonds.

7. The method of claim 1 , wherein said photoactive linker comprises C—H bonds, N—H bonds, or S—H bonds.

8. The method of claim 7 , wherein said photoactive groups of the photoactive linker react through the C—H bonds, N—H bonds, or S—H bonds upon said irradiating.

9. The method of claim 1 , further comprising depositing additional photoactive nanoparticles after said depositing the photoactive nanoparticles to the surface of the substrate.

10. The method of claim 1 , wherein the substrate comprises glass, silicon or gold.

11. The method of claim 10 , wherein the substrate comprises glass.

12. A method to obtain a functionalized surface, the method comprising:
attaching a plurality of photoactive linkers to a plurality of nanoparticles to obtain photoactive nanoparticles, wherein each linker comprises a binding group that attaches to the nanoparticle and a photoactive group, and wherein the photoactive group comprises a phthalimide or benzophenone group;
depositing the photoactive nanoparticles to the surface of the substrate, wherein the surface of the substrate comprises hydrogen-containing reactive groups; and
irradiating the photoactive nanoparticles in the presence of a substrate having hydrogen-containing reactive groups such that the photoactive group reacts with the substrate, thereby forming a functionalized surface on the substrate.

13. The method of claim 12 , further comprising applying a mask having a pre-selected pattern to the surface of the substrate prior to said irradiating.

14. The method of claim 12 , wherein the nanoparticles are selected from the group consisting of metal oxide nanoparticles, gold nanoparticles, quantum dots, magnetic nanoparticles, photonic nanoparticles, and drug delivery nanoparticles.

15. The method of claim 12 , wherein the nanoparticles have at least one dimension of about 10 to about 100 nm.

16. The method of claim 12 , wherein the photoactive linker further comprises a spacer.

17. The method of claim 12 , wherein the substrate comprises an organic material comprising C—H bonds, N—H bonds, or S—H bonds.

18. The method of claim 12 , wherein the substrate comprises glass, silicon or gold.

19. The method of claim 18 , wherein the substrate comprises glass.

20. The method of claim 12 , further comprising depositing additional photoactive nanoparticles after said depositing the photoactive nanoparticles to the surface of the substrate.

21. A method for functionalizing a surface of a substrate with nanoparticles, the method comprising:
attaching a plurality of photoactive linkers to a plurality of nanoparticles to obtain photoactive nanoparticles, wherein each linker comprises a binding group that attaches to the nanoparticle and a photoactive group, and wherein the nanoparticles are drug delivery nanoparticles;
depositing the photoactive nanoparticles to the surface of the substrate, wherein the surface of the substrate comprises hydrogen-containing reactive groups; and
irradiating the photoactive nanoparticles in the presence of a substrate having hydrogen-containing reactive groups such that the photoactive group reacts with the substrate, thereby forming a functionalized surface on the substrate.

22. The method of claim 21 , further comprising applying a mask having a pre-selected pattern to the surface of the substrate prior to said irradiating.

23. The method of claim 21 , wherein the nanoparticles have at least one dimension of about 10 to about 100 nm.

24. The method of claim 21 , wherein the photoactive linker further comprises a spacer.

25. The method of claim 21 , wherein the substrate comprises an organic material comprising C—H bonds, N—H bonds, or S—H bonds.

26. The method of claim 21 , wherein said photoactive linker comprises C—H bonds, N—H bonds, or S—H bonds.

27. The method of claim 26 , wherein said photoactive groups of the photoactive linker react through the C—H bonds, N—H bonds, or S—H bonds upon said irradiating.

28. The method of claim 21 , further comprising depositing additional photoactive nanoparticles after said depositing the photoactive nanoparticles to the surface of the substrate.

29. The method of claim 21 , wherein the substrate comprises glass, silicon or gold.

30. The method of claim 29 , wherein the substrate comprises glass.

Assignees

• Park Ellane J
• Turro Nicholas J
• Koberstein Jeffrey T
• Univ Columbia

Inventors

• Park Ellane J
• Turro Nicholas J
• Koberstein Jeffrey T

Classifications

• C09D1/00

  Coating compositions, e.g. paints, varnishes or lacquers, based on inorganic substances · CPC title

• C09D7/1266

  Chemistry & Metallurgy · mapped topic

• C08J7/18 Primary

  using wave energy or particle radiation · CPC title

• C08J2325/06

  Polystyrene · CPC title

• C09D7/1225

  Chemistry & Metallurgy · mapped topic