Radiomic signature of a perivascular region
US-2024404058-A1 · Dec 5, 2024 · US
US9295432B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9295432-B2 |
| Application number | US-201314434410-A |
| Country | US |
| Kind code | B2 |
| Filing date | Oct 10, 2013 |
| Priority date | Oct 19, 2012 |
| Publication date | Mar 29, 2016 |
| Grant date | Mar 29, 2016 |
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A method of determining a distribution of a dose in a body is presented including the steps of scanning at least one region of the body to extract image data, calculating a plurality of parameters from the image data, and entering a plurality of computed tomography (CT) scan parameters. The method also includes the steps of calculating radiation distribution by using a local interaction principle and creating a three-dimensional dose map based on the calculated radiation distribution.
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The invention claimed is: 1. A method of determining a radiation distribution of a dose in a body, the method comprising: scanning at least one region of the body to extract image data, wherein the image data is represented as a plurality of three-dimensional cubic voxels; calculating a plurality of parameters from the image data; entering a plurality of computed tomography (CT) scan parameters; calculating the radiation distribution by using a customized local interaction principle, which calculates a radiant flux of the plurality of three-dimensional cubic voxels by measuring radiant fluxes flowing between neighboring cubic voxels of the plurality of three-dimensional cubic voxels; and creating a three-dimensional dose map based on the calculated radiation distribution. 2. The method according to claim 1 , further comprising rescaling the image data. 3. The method according to claim 1 , further comprising representing the image data as either a 64×64 voxel grid or a 128×128 voxel grid in an x-y plane. 4. The method according to claim 1 , wherein the radiation distribution indicates an energy absorbed in every voxel. 5. The method according to claim 1 , wherein the plurality of CT scan parameters includes at least one of attenuation factors, phase function factors, and scattering factors. 6. The method according to claim 1 , further comprising computing the radiation distribution in six directions for scattering according to the following formula: I + x ( i , j , k ) = T ( i , j , k ) * I + x ( i - 1 , j , k ) + R ( i , j , k ) * I - x ( i + 1 , j , k ) + S ( i , j , k ) * ( I + y ( i , j - 1 , k ) + I - y ( i , j + 1 , k ) + I + z ( i , j , k - 1 ) + I - z ( i , j , k + 1 ) ) where 1 represents radiant flux, i, j and k are unit vect
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